{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:15:19Z","timestamp":1787015719271,"version":"build-2736575974"},"reference-count":59,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The detrimental effects of hyperthermia on the testes and the protective effect of thyme essential oil against testicular damage induced by this stress in rams were studied. Twenty\u2010four rams of the Barbarine breed with an average weight of 62.5\u2009\u00b1\u20090.3\u2009kg and an average age of 24\u2009\u00b1\u20090.6 months. The experiment consisted of inducing localized heat stress on the first group of rams by applying heat bags to both testicles of six rams (G s). The second group underwent the same heat stress on the testes but received orally 100\u2009\u00b5L\/day\/animal of thyme essential oil (G s\u2010he). A positive control did not undergo stress but received thyme essential oil (G he) with the same doses as the (G s\u2010he) group, and the negative control did not undergo either stress or receive the essential oil of thyme (G c). One hundred twenty\u2010eight adult ewes of the same breed divided into four groups of 32 ewes were used to study the effect of different treatments on the in vivo ram's fertility. Ewes are synchronized and we have applied natural mating with oestrus control, the reproduction balance sheet is calculated after lambing. The results showed that tests of heat stress (HS) negatively affect semen quality but did not cause infertility. However, neither tests for heat stress nor treatment with thyme EO significantly affected the haematological profile. The study of the effect of heat stress on the testes on fertility in vivo showed a drop in the number of females who were fertilized at the first oestrus and consequently a drop in fertility. However, the rams that suffered the same stress but were treated with EO thymus recorded an improvement in these parameters.<\/jats:p>","DOI":"10.1111\/jpn.14063","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T14:27:53Z","timestamp":1730125673000},"page":"437-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Antioxidant Capacity of Thyme (\n                    <i>Thymus vulgaris<\/i>\n                    ) Essential Oil and Its Effect on In Vivo Fertility of Rams Subjected to Testicle Heat Stress"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5277-3262","authenticated-orcid":false,"given":"Samia","family":"Khnissi","sequence":"first","affiliation":[{"name":"Laboratory of Animal and Forage Production National Institute of Agronomic Research of Tunisia (INRAT) University of Carthage Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Im\u00e8ne","family":"Ben Salem","sequence":"additional","affiliation":[{"name":"Department of Animal Production, Service of Zootechnics and Agricultural Economy National School of Veterinary Medicine Sidi Thabet University of Manouba Cit\u00e9 Nasr Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bochra","family":"Bejaoui","sequence":"additional","affiliation":[{"name":"Laboratory of Useful Materials National Institute of Research and Pysico\u2010Chemical Analysis (INRAP), Technopark of Sidi Thabet Ariana Tunisia"},{"name":"Department of Chemistry University of Carthage, Faculty of Sciences of Bizerte Bizerte Zarzouna Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Fattouch","sequence":"additional","affiliation":[{"name":"EcoChemistry Laboratory, National Institute of Applied Sciences and Technology (INSAT) University of Carthage Carthage Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souha ben","family":"Mustapha","sequence":"additional","affiliation":[{"name":"EcoChemistry Laboratory, National Institute of Applied Sciences and Technology (INSAT) University of Carthage Carthage Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami","family":"Haj\u2010Kacem","sequence":"additional","affiliation":[{"name":"Tunisia Polytechnic School, LEGI University of Carthage Carthage Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naceur","family":"M'Hamdi","sequence":"additional","affiliation":[{"name":"Research Laboratory of Ecosystems and Aquatic Resources, National Agronomic Institute of Tunisia Carthage University Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Martin","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Transformations and Agroressources, ULR7519 Universit\u00e9 d'Artois\u2010UniLaSalle B\u00e9thune France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Dattena","sequence":"additional","affiliation":[{"name":"Department of Animal Science Agricultural Research Agency of Sardinia Olmedo Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narjess","family":"Lassoued","sequence":"additional","affiliation":[{"name":"Laboratory of Animal and Forage Production National Institute of Agronomic Research of Tunisia (INRAT) University of Carthage Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"11636","DOI":"10.5897\/AJB12.225","article-title":"Aqueous Ethanolic Extract of Cochlospermum planchonii Rhizome Enhances Spermatogenesis in Male Albino Rats","volume":"11","author":"Abu A. H.","year":"2012","journal-title":"African Journal of Biotechnology"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9090601"},{"key":"e_1_2_9_4_1","volume-title":"Manuel de formation pour l'ins\u00e9mination artificielle chez les ovins et les caprins","author":"Baril G.","year":"1993"},{"issue":"3","key":"e_1_2_9_5_1","first-page":"910","article-title":"Thermoregulation and Reproductive Responses of Rams Under Heat Stress: Review","volume":"12","author":"Barrag\u00e1n Sierra A.","year":"2021","journal-title":"Revista Mexicana de Ciencias Pecuarias"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2019.09.026"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"1","article-title":"Significance of Hypothalamic\u2010Pituitary\u2010Adrenal Axis to Adapt to Climate Change in Livestock","volume":"2","author":"Binsiya T.","year":"2017","journal-title":"International Journal of Research in Agricultural and Food Science"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.23123"},{"key":"e_1_2_9_9_1","first-page":"156","article-title":"Improvement of Antioxidant Status and Semen Quality by Oral Supplementation With Vitamins C and E in Rams","volume":"26","author":"Cofr\u00e9\u2010Narbona E. J.","year":"2016","journal-title":"Revista Cient\u00edfica"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2478\/aoas-2014-0084"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2013.12.041"},{"key":"e_1_2_9_12_1","first-page":"71","article-title":"Reproductive Traits of Male Weaner Rabbits Fed Graded Leaves of Garcina kola (Bitter kola)","volume":"1","author":"Ebenebe C. I.","year":"2017","journal-title":"Nigerian Journal of Animal Science"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4995\/wrs.2014.1677"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejap.1981.128852"},{"key":"e_1_2_9_15_1","unstructured":"Fahmy S. 1994. \u201cEffect of Crossing Romanov With Rahmani Sheep on Some Physiological and Productive Performance.\u201d M.Sc. thesis Faculty of Agriculture Al\u2010Azhar University."},{"issue":"1","key":"e_1_2_9_16_1","first-page":"41","article-title":"Water and Alcohol Extraction of Thyme Plant (Thymus vulgaris) and Activity Study Against Bacteria, Tumors and Used as Anti\u2010Oxidant in Margarine Manufacture","volume":"4","author":"Fayad N. K.","year":"2013","journal-title":"Innovative Systems Design and Engineering"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00484-020-01917-w"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.55544\/jrasb.2.1.9"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1007"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2019.12.005"},{"key":"e_1_2_9_21_1","first-page":"231","article-title":"Physiological Indicators of Adaptation in Awassi and Finn x Texel x Awassi Sheep","volume":"33","author":"Hamadeh S. K.","year":"1997","journal-title":"Options Mediterraneennes. Serie A: Seminaires Mediterraneens (CIHEAM)"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1687657"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.112.016584"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00580-017-2434-2"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1210595"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2018.01.015"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10735-009-9222-5"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.3293"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.7763\/IJESD.2014.V5.503"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12340"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/09291016.2017.1299364"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2004.05.056"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2008.00382"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0722710"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2006.10.003"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.2527\/2003.812395x"},{"issue":"2","key":"e_1_2_9_37_1","first-page":"71","article-title":"Proximate and Phytochemical Analysis of Cochlospermum Planchonii Rhizome","volume":"12","author":"Mhomga L. I.","year":"2019","journal-title":"Journal of Agriculture and Veterinary Sciences"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2019.1666804"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2018.09.037"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtherbio.2017.01.001"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.18502\/ijrm.v20i7.11559"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.7897\/2277-4572.031102"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.13601"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods9091221"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11071330"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1556\/avet.2013.012"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/761264"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12133"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/929285"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2015.07.008"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2007.07.007"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2021.151712"},{"key":"e_1_2_9_53_1","first-page":"13","article-title":"Extracts From Thymus vulgaris and Origanum vulgare L. Obtained by Different Separation Processes: Global Yield and Functional Profile","volume":"2","author":"Sena S. R.","year":"2018","journal-title":"Trends in Phytochemical Research"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejap.1984.108865"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0921-4488(03)00097-x"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2021.06.045"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.5398\/medpet.2017.40.2.88"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12676"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.005132"},{"issue":"2","key":"e_1_2_9_60_1","first-page":"263","article-title":"Antioxidant Effects of Thyme (Thymus vulgaris) Extract on Ram Sperm Quality During Cryopreservation","volume":"8","author":"Vahedi V.","year":"2018","journal-title":"Iranian Journal of Applied Animal Science"}],"container-title":["Journal of Animal Physiology and Animal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpn.14063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:13:09Z","timestamp":1742343189000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpn.14063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,28]]},"references-count":59,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/jpn.14063"],"URL":"https:\/\/doi.org\/10.1111\/jpn.14063","archive":["Portico"],"relation":{},"ISSN":["0931-2439","1439-0396"],"issn-type":[{"value":"0931-2439","type":"print"},{"value":"1439-0396","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,28]]},"assertion":[{"value":"2024-01-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}