{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:02:42Z","timestamp":1787238162389,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:00:00Z","timestamp":1733616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study investigated expressions of microRNA (miR)\u201026a, miR\u201027a, and miR\u2010148a in plasma, colostrum and milk collected on different days (0th, 4th, 7th, 14th, and 28th days) during transition from colostrum to milk in Awassi sheep. Relationships between miRNAs and quality parameters were also explored. During transition, Somatic Cell Count, Fat\u2010free dry matter, protein, lactose decreased, pH, freezing point (FP), electrical conductivity (EC) increased. Malondialdehydes (MDA) were tended to decrease in plasma and milk. Compared to 0th day, miR\u201026a was upregulated approximately 27\u2010folds and 17\u2010folds in 14th and 28th days, in milk. On 14th day, miR\u201027a showed almost 18\u2010folds upregulation, while miR\u2010148a was downregulated more than fivefolds on 7th and 14th days. In plasma, miR\u201026a was upregulated almost 40\u2010folds and sevenfolds on 7th and 14th days. Additionally, miR\u201027a was upregulated by approximately fivefolds on 4th day, around 20\u2010folds on 7th day, and about fourfolds on 14th day. miR\u2010148a was upregulated approximately 11\u2010folds on 7th day. While miR\u201026a positively correlated with miR\u201027a, pH, fat, and EC, it was negatively correlated with MDA in plasma. miR\u201027a was positively correlated with miR\u2010148a and pH. Plasma miR\u2010148a and milk miR\u2010148a were negatively correlated. miR\u201026a and miR\u201027a were positively correlated in milk. Milk miR\u201026a was positively correlated with pH, FP, and EC, while it was negatively correlated with fat, milk and plasma MDA. Milk miR\u201027a was negatively correlated with fat and MDA, but positively with EC. The results obtained for the first\u2010time during transition indicate potentials of miR\u201026a and miR\u201027a to act as biomarkers for sheep milk quality.<\/jats:p>","DOI":"10.1111\/jpn.14078","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T01:48:42Z","timestamp":1733708922000},"page":"623-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dynamics of Selected Milk Quality Parameters and Expression Patterns of miR\u201026a, miR\u201027a, and miR\u2010148a During Transition From Colostrum to Mature Milk in Awassi Sheep"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5753-8985","authenticated-orcid":false,"given":"H\u00fcseyin","family":"\u00d6zkan","sequence":"first","affiliation":[{"name":"Department of Genetics Faculty of Veterinary Medicine Hatay Mustafa Kemal University Antakya Hatay 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