{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:39:47Z","timestamp":1789486787944,"version":"build-2803163510"},"reference-count":64,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    While \u03b2\u2010glucans from plants and yeasts have been extensively studied in weaned piglets, studies examining algae \u03b2\u2010glucans are scarce. Thus, the present study aimed to examine the effects of feeding algae \u03b2\u2010glucan in weaned piglets. Male, 21\u2010day\u2010old, weaned crossbred piglets were allotted to three experimental groups, which were fed either an adequate basal diet (Control) or the basal diet supplemented with 100 (A100) or 200\u2009g\/t (A200) of algae \u03b2\u2010glucan for 35 days. Performance parameters, apparent total tract digestibility of nutrients, gut morphology metrics, gut mucosa mRNA levels of most genes involved in gut function and integrity, and the number of different immune cells in the proximal jejunum did not differ across groups after 35 days. In the mid\u2010jejunum, the number of lymphocytes in the\n                    <jats:italic>lamina propria<\/jats:italic>\n                    was higher in the A200 group than in the other two groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) after 35 days. Mucosa score for mucosa fibrosis, villous stunting and villous epithelial injury in the duodenum and the proximal and mid\u2010jejunum were not different across groups after 35 days. The proportion of acetate was higher, and that of valerate was lower in the colon digesta of the A200 group than in the other two groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). While the abundance of\n                    <jats:italic>Prevotella<\/jats:italic>\n                    spp. was lower in the A200 group than in the other groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), the abundance of\n                    <jats:italic>Bifidobacterium<\/jats:italic>\n                    spp.,\n                    <jats:italic>Clostridium\u2010leptum<\/jats:italic>\n                    \u2010group,\n                    <jats:italic>Faecalibacterium prausnitzii<\/jats:italic>\n                    and\n                    <jats:italic>Lactobacillus<\/jats:italic>\n                    spp. in the colon digesta did not differ across groups after 35 days. In conclusion, feeding algae \u03b2\u2010glucan to healthy weaned piglets marginally influences gut\u2010associated parameters and the abundance of selected bacterial groups and the bacterial fermentation pattern in the colon digesta but has no effect on growth performance.\n                  <\/jats:p>","DOI":"10.1111\/jpn.70077","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T18:54:33Z","timestamp":1779303273000},"page":"642-654","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Algae \u03b2\u2010Glucan Supplementation on the Performance and Intestinal Immune System of Healthy Weaned Piglets"],"prefix":"10.1111","volume":"110","author":[{"given":"Johanna O.","family":"Buckenberger","sequence":"first","affiliation":[{"name":"Institute of Animal Nutrition and Nutritional Physiology Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felizitas","family":"Gut\u00f6hrlein","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition and Nutritional Physiology Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Henrich","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Pathology Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Most","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition and Nutritional Physiology Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Whelan","sequence":"additional","affiliation":[{"name":"Evonik Operations GmbH Hanau\u2010Wolfgang Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Htoo","sequence":"additional","affiliation":[{"name":"Evonik Operations GmbH Hanau\u2010Wolfgang Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Ringseis","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition and Nutritional Physiology Justus Liebig University Giessen Giessen Germany"},{"name":"Center for Sustainable Food Systems Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Eder","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition and Nutritional Physiology Justus Liebig University Giessen Giessen Germany"},{"name":"Center for Sustainable Food Systems Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2016.02.004"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2021.1996830"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani14040631"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23158301"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.9.2256"},{"key":"e_1_2_10_7_1","first-page":"453","article-title":"Analytik von TiO2 in Darminhalt und Kot nach Kjeldahlaufschluss","volume":"37","author":"Brandt M.","year":"1987","journal-title":"Archives of Animal Nutrition"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2008-1330"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.2000.00013.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/2049-1891-4-19"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201600032"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0739-7240(98)00006-X"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.31989\/ffhd.v5i11.209"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016-12406"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2008.04.008"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2008.01.001"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.01.009"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-014-0196-5"},{"key":"e_1_2_10_19_1","first-page":"354","article-title":"The Role of Neutrophils During Intestinal Inflammation","volume":"5","author":"Fournier B. 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