{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:10:56Z","timestamp":1791562256304,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Over recent years the use of yeast in feedstuffs has gained momentum due to novel developments in single\u2010cell proteins (SCPs). SCPs are considered a sustainable protein source, as their production enable to convert low\u2010value substrates (including industrial\/agricultural wastes) into feed, with a related reduced environmental impact. This study provides a first\u2010step insight into the dietary inclusion of torula yeast\u2010derived SCPs in broiler chicken diets. A total of 720 1\u2010day\u2010old male broilers were divided into four groups (10 replicate pens\/group): the control group (CON) received a commercial soybean\u2010based diet, while the SCP groups (SCP2, SCP4, SCP6) were fed diets supplemented with 2%, 4%, or 6% SCPs during the grower and finisher phases (15\u201342\u2009d) as a partial replacement for soybean meal. Growth performance, footpad dermatitis (FPD), plasma metabolome, and breast\u2010meat quality and composition were evaluated. For the entire trial period, performance traits and FPD rates did not differ significantly, however a trend was observed for body weight and daily weight gain which tended to decrease with increasing SCP levels (3083, 3058, 2988, 2942\u2009g\/bird, and 72.1, 71.6, 69.8, 68.8\u2009g\/bird\/day respectively for CON, SCP2, SCP4, and SCP6;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.071; linear fit &lt;\u20090.01). Breast\u2010meat quality and composition were maintained apart from linearly increased yellowness (b*) in CON, SCP2, SCP4, and SCP6 (7.67, 8.57, 9.11, and 10.38;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001; linear fit &lt;\u20090.01). As for plasma metabolites, focusing on differences attributable to SCPs inclusion levels, on day 21, SCP6 reduced Threonine (\u221234%) and increased Isoleucine (+26%), Ethanol (+91%), Uridine (+67%), Leucine (+24%), and 2,3\u2010butanediol (+60%) compared with CON (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). At day 42, SCP6 reduced Arginine (\u221246%) and Threonine (\u221217%) and increased 2\u2010aminobutyrate (+51%), Uridine (+116%), Trans\u20104\u2010hydroxy\u2010L\u2010proline (+29%), and Formate (+25%) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2264\u20090.05). Overall, the findings demonstrate the feasibility of graded SCPs inclusion in broiler diets, with a potential upper limit of 4%, as indicated by changes in performance and plasma metabolome.\n                  <\/jats:p>","DOI":"10.1111\/jpn.70082","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:29:15Z","timestamp":1780378155000},"page":"674-684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Torula Yeast (\n                    <i>Candida utilis<\/i>\n                    ) Single Cell Proteins as a Partial Replacement for Soybean Meal in Broiler Diets: Effects on Productive Performance, Meat Quality Traits, and Plasma Metabolome"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1754-8270","authenticated-orcid":false,"given":"Jonathan","family":"Dayan","sequence":"first","affiliation":[{"name":"Department of Agricultural and 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Mater Studiorum \u2010 University of Bologna Cesena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1562-2040","authenticated-orcid":false,"given":"Elisa","family":"Benini","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Sciences Alma Mater Studiorum \u2010 University of Bologna Cesena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5671-5676","authenticated-orcid":false,"given":"Massimiliano","family":"Petracci","sequence":"additional","affiliation":[{"name":"Department of Agricultural and Food Sciences Alma Mater Studiorum \u2010 University of Bologna Cesena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4640-7346","authenticated-orcid":false,"given":"Federico","family":"Sirri","sequence":"additional","affiliation":[{"name":"Department of Agricultural and Food Sciences Alma Mater Studiorum 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