{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:41:30Z","timestamp":1789731690572,"version":"4.0.1"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T00:00:00Z","timestamp":1350864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Studies performed over the last 15\u00a0years have suggested that periodontal diseases may be associated with adverse pregnancy outcomes. However, this association has not been found in all populations. The aim of this study was to evaluate whether periodontal status and the presence of specific periodontal pathogens may influence the incidence of adverse pregnancy outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Pregnant women were clinically examined before 26th week of gestation, and divided in two groups: non\u2010periodontitis and periodontitis. Microbial samples were obtained in the periodontitis group and processed by anaerobic culturing. After delivery, data on the pregnancy outcome were taken; mother's socio\u2010demographic and risk factors were obtained at inclusion. Simple and multiple regression analysis were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and seventy women were included in the study (116 non\u2010periodontitis and 54 with periodontitis). The incidence of preterm (<jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content>) and low\u2010birth weight (<jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content>) was 2.94% and 3.53%, respectively. Periodontal status did not show any association with adverse pregnancy outcomes. The presence of <jats:italic>Eikenella corrodens<\/jats:italic> was significantly related to <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.022) and the presence <jats:italic>Capnocytophaga<\/jats:italic> spp. was related to <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content> (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.008). The multivariate analyses showed a significant association between <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> and newborn weight and counts of <jats:italic>E.\u00a0corrodens<\/jats:italic>. Maternal health and counts of <jats:italic>E.\u00a0corrodens<\/jats:italic> were significantly associated with <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical periodontal condition was not associated with adverse pregnancy outcomes in a <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish Caucasian population with medium\u2010high educational level. The presence and counts of <jats:italic>E.\u00a0corrodens<\/jats:italic> and the presence of <jats:italic>Capnocytophaga<\/jats:italic> spp. showed a significant association with <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content>, respectively, in the bivariate and\/or multivariate model.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jre.12024","type":"journal-article","created":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T06:51:23Z","timestamp":1350888683000},"page":"443-451","source":"Crossref","is-referenced-by-count":35,"title":["Association between periodontal status and pre\u2010term and\/or low\u2010birth weight in <scp>S<\/scp>pain: clinical and microbiological parameters"],"prefix":"10.1111","volume":"48","author":[{"given":"I.","family":"Santa Cruz","sequence":"first","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group University Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Herrera","sequence":"additional","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group University Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Martin","sequence":"additional","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group University Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Herrero","sequence":"additional","affiliation":[{"name":"Section of Periodontology School of Dentistry University Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sanz","sequence":"additional","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group University Complutense Madrid 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