{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T23:27:55Z","timestamp":1782689275052,"version":"3.54.5"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T00:00:00Z","timestamp":1358121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The treatment of molar furcation defects remains a considerable challenge in clinical practice. The identification of clinical measurements influential to treatment outcomes is critical to optimize the results of surgical periodontal therapy. The present study aimed to explore the clinical and radiographical effectiveness of autologous platelet\u2010rich fibrin (<jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content>) and autologous platelet\u2010rich plasma (<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content>) in the treatment of mandibular degree <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> furcation defects in subjects with chronic periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Seventy\u2010two mandibular degree <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> furcation defects were treated with either autologous <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> with open flap debridement (<jats:styled-content style=\"fixed-case\">OFD<\/jats:styled-content>; 24 defects) or autologous <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">OFD<\/jats:styled-content> (25), or <jats:styled-content style=\"fixed-case\">OFD<\/jats:styled-content> alone (23). Clinical and radiological parameters such as probing depth, relative vertical clinical attachment level and horizontal clinical attachment level along with gingival marginal level were recorded at baseline and 9\u00a0mo postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All clinical and radiographic parameters showed statistically significant improvement at both the test sites (<jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">OFD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">OFD)<\/jats:styled-content> compared to those with <jats:styled-content style=\"fixed-case\">OFD<\/jats:styled-content> alone. <jats:styled-content style=\"fixed-case\">Relative vertical clinical attachment level<\/jats:styled-content> gain was also greater in <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> (2.87\u00a0\u00b1\u00a00.85\u00a0mm) and <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> (2.71\u00a0\u00b1\u00a01.04\u00a0mm) sites as compared to control site (1.37\u00a0\u00b1\u00a00.58\u00a0mm), and <jats:styled-content style=\"fixed-case\">relative horizontal clinical attachment level<\/jats:styled-content> gain was statistically significantly greater in both <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> than in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of autologous <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> were both effective in the treatment of furcation defects with uneventful healing of sites.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jre.12040","type":"journal-article","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T14:20:11Z","timestamp":1358173211000},"page":"573-581","source":"Crossref","is-referenced-by-count":83,"title":["Comparative evaluation of autologous platelet\u2010rich fibrin and platelet\u2010rich plasma in the treatment of mandibular degree II furcation defects: a randomized controlled clinical trial"],"prefix":"10.1111","volume":"48","author":[{"given":"Pavan","family":"Bajaj","sequence":"first","affiliation":[{"name":"Department of Periodontics Government Dental College &amp; Research Institute Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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