{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:23:49Z","timestamp":1753439029803,"version":"3.40.5"},"reference-count":49,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T00:00:00Z","timestamp":1580083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18K17061"],"award-info":[{"award-number":["18K17061"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The present study aimed to evaluate the histological outcome of tunnel \u03b2\u2010TCP blocks grafting in extraction sockets missing the buccal bone wall, after 6\u00a0months of healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Tunnel \u03b2\u2010tricalcium phosphate (\u03b2\u2010TCP) blocks made of randomly organized tunnel\u2010shaped \u03b2\u2010TCP ceramics appeared promising for alveolar ridge preservation in tooth extraction sockets missing the buccal bone, in a previous study in dogs, with a 2\u2010month healing time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In six beagle dogs, the maxillary first premolars were extracted and the buccal bone was surgically removed to create bone defects of 4\u00a0mm (mesio\u2010distal)\u00a0\u00d7\u00a05\u00a0mm (apico\u2010coronal)\u00a0\u00d7\u00a04\u00a0mm (bucco\u2010palatal). Thus, extraction sockets missing the buccal bone plate were grated with tunnel \u03b2\u2010TCP blocks (test) or left empty for spontaneous healing (control). Histology\/histomorphometry was performed after 6\u00a0months of healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The horizontal bucco\u2010palatal width of the alveolar ridge was significantly greater at test sites than at control sites. The amount of mineralized tissue was greater at test sites (57.8%\u00a0\u00b1\u00a011.1%) than at control sites (28.9%\u00a0\u00b1\u00a08.5%), while the amount of connective tissue was significantly greater at control sites (41.7%\u00a0\u00b1\u00a06.4%) than at test sites (19.6%\u00a0\u00b1\u00a09.2%). No significant difference was found between sites in terms of basic multicellular units and bone marrow. Residual \u03b2\u2010TCP at test sites was 5.8%\u00a0\u00b1\u00a03.2%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Grafting with tunnel \u03b2\u2010TCP block significantly limited the resorption of the alveolar ridge at extraction sockets missing the buccal bone compared with sites left to heal spontaneously, even after 6\u2010month follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jre.12735","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T10:29:40Z","timestamp":1580120980000},"page":"496-502","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ridge reconstruction in damaged extraction sockets using tunnel \u03b2\u2010tricalcium phosphate blocks: A 6\u2010month histological study in beagle dogs"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9862-4281","authenticated-orcid":false,"given":"Takahiro","family":"Ikawa","sequence":"first","affiliation":[{"name":"Department of Periodontology Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan"},{"name":"Department of Periodontology Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Akizuki","sequence":"additional","affiliation":[{"name":"Department of Periodontology Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Periodontology Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo 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