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Compounds were administered daily via intraperitoneal injection over a 20\u2010day period. Periodontitis was induced with the bilateral insertion of ligatures around the first lower molars of each rat. Oral parameters, as well as blood biomarkers, were measured: histopathological assessment of the hepatic tissue was carried out using light and transmission electron microscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The treatment with \u03b1TPN\u2010\u03b2CD significantly improved several oral parameters and blood biomarkers in comparison with rats with periodontitis. In addition, the treatment with \u03b1TPN\u2010\u03b2CD significantly ameliorated the steatosis score and reduced the number of lipid droplets and the amount of foamy cytoplasm in the hepatocytes of rats with periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results obtained suggest that the treatment with \u03b1TPN\u2010\u03b2CD improves several oral and blood parameters in rats with experimental periodontitis. In addition, hepatic alterations caused by periodontitis were ameliorated in the rats treated with \u03b1TPN\u2010\u03b2CD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jre.12780","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T10:52:20Z","timestamp":1593082340000},"page":"877-886","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Alpha\u2010terpineol complexed with beta\u2010cyclodextrin reduces damages caused by periodontitis in rats"],"prefix":"10.1111","volume":"55","author":[{"given":"Any Carolina Cardoso Guimar\u00e3es","family":"Vasconcelos","sequence":"first","affiliation":[{"name":"Medicinal Plants Research Center (NPPM) Federal University of hPiaui Teresina Brazil"},{"name":"Medicine School Education Institute of Parnaiba Valley (IESVAP\u2010Afya) Parnaiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Fernando 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