{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T10:38:52Z","timestamp":1792406332002,"version":"4.4.0"},"reference-count":63,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>This randomized trial assessed for the first time the efficacy of coronally advanced flap (CAF) followed by micro\u2010needling (MN) in contrast to CAF with acellular dermal matrix (ADM) on gingival thickness (GT, primary outcome), keratinized tissue width (KTW), clinical attachment level (CAL), probing depth (PD), recession depth (RD), recession width (RW), recession reduction (Rec\u2010Red), complete root coverage (CRC) and percentage of root coverage (all secondary outcomes) in management of RT1 gingival recession in patients with thin gingival phenotype.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 24 patients (<jats:italic>n<\/jats:italic>\u2009=\u200924) with a thin gingival phenotype and single RT1 gingival recession in the aesthetic zone were randomly allocated to test\u2010 (CAF\u2009+\u2009MN; <jats:italic>n<\/jats:italic>\u2009=\u200912) or control group (CAF\u2009+\u2009ADM; <jats:italic>n<\/jats:italic>\u2009=\u200912). All clinical parameters were evaluated at baseline, 3 and 6\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both groups independently demonstrated significant gain in GT, RW, RD, CAL, PD, Rec\u2010Red, CRC and percentage of root coverage, with reduced PI and BOP (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) at 3 and 6\u2009months, without intergroup differences (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). At 6\u2009months, KTW gain was significantly higher in CAF\u2009+\u2009MN (5.08\u2009\u00b1\u20090.9\u2009mm) than in CAF\u2009+\u2009ADM\u2010group (4.25\u2009\u00b1\u20091.06\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Stepwise linear regression model with GT as dependent variable showed that base\u2010line GT was the only statistically significant predictor for GT with a direct correlation between base\u2010line GT and GT after 6\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CAF followed by MN could represent a promising graft\u2010less approach for increasing gingival thickness, comparable to CAF with ADM, with superior keratinized tissue width improvement, in the treatment of RT1 recession defects in patients with thin gingival phenotype.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jre.13271","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T09:40:17Z","timestamp":1714038017000},"page":"907-917","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Micro\u2010needling versus acellular dermal matrix in <scp>RT1<\/scp> gingival recession coverage: A randomized clinical trial"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3250-8436","authenticated-orcid":false,"given":"Salma","family":"Zaaya","sequence":"first","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1818-0321","authenticated-orcid":false,"given":"Weam","family":"Elbattawy","sequence":"additional","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1433-2523","authenticated-orcid":false,"given":"Sarah","family":"Yusri","sequence":"additional","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6261-3609","authenticated-orcid":false,"given":"Karim M.","family":"Fawzy\u00a0El\u2010Sayed","sequence":"additional","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"},{"name":"Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine Christian Albrechts University  Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.150625"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00434.x"},{"issue":"1","key":"e_1_2_13_4_1","first-page":"119","article-title":"Correlation between gingival biotype and occurrence of gingival recession","volume":"5","author":"Singh M","year":"2020","journal-title":"Saudi J Oral Dent Res"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12205"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"issue":"1","key":"e_1_2_13_7_1","article-title":"What happens to an acellular dermal matrix after implantation in the human body? 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