{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T16:38:28Z","timestamp":1793032708954,"version":"4.5.0"},"reference-count":47,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100007619","name":"Osteology Foundation","doi-asserted-by":"publisher","award":["20127"],"award-info":[{"award-number":["20127"]}],"id":[{"id":"10.13039\/501100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This split\u2010mouth randomized clinical trial aimed to assess whether incorporating platelet\u2010rich fibrin (PRF) into a volume\u2010stable collagen matrix results in superior reduction of recession depth after 6\u2009months of healing in the treatment of multiple gingival recessions using the coronally advanced flap.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with bilateral maxillary RT1 recessions at non\u2010molar sites were recruited. Each side received either a PRF\u2010impregnated matrix or a non\u2010impregnated matrix. Clinical parameters, including recession depth, keratinized tissue width, bleeding on probing, probing depth, clinical attachment level, and gingival thickness, were measured at baseline and 6\u2009months, as well as the Root Coverage Esthetic Score (RES) and patient\u2010reported outcome measures (PROMs). The percentage of complete root coverage was calculated 6\u2009months after treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010five patients were enrolled. However, one patient was excluded due to incomplete follow\u2010up. Both groups significantly improved over time, but no intergroup differences were observed for any of the clinical parameters (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). No statistically significant differences were found between test and control groups in evaluations of RES and PROMs, showing similar postoperative experiences of patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within the limitations of this study, adding PRF to a volume\u2010stable collagen matrix did not result in superior recession depth reduction or improved clinical, esthetic, or patient\u2010reported outcomes after 6\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      Brazilian Register of Clinical Trials (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/ensaiosclinicos.gov.br\">ensaiosclinicos.gov.br<\/jats:ext-link>\n                      ) identifier: RBR\u20103hqrvrr (20\/10\/2021)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jre.70127","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T11:49:48Z","timestamp":1782388188000},"page":"929-943","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Volume\u2010Stable Collagen Matrix With or Without Platelet\u2010Rich Fibrin Impregnation for Multiple Gingival Recessions: A Randomized Clinical Trial"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0724-0560","authenticated-orcid":false,"given":"Gabriel Leonardo","family":"Magrin","sequence":"first","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4882-0852","authenticated-orcid":false,"given":"Roberta","family":"Michels","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"},{"name":"Department of Periodontology University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Clara Kuerten","family":"Gil","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1873-135X","authenticated-orcid":false,"given":"Kelly Batista","family":"Maier","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6102-8566","authenticated-orcid":false,"given":"Bruna","family":"Mueller","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5400-9009","authenticated-orcid":false,"given":"Reinhard","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Oral Biology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Augusto Magalh\u00e3es","family":"Benfatti","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2025.105645"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.98"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"issue":"2","key":"e_1_2_11_5_1","first-page":"S8","article-title":"Periodontal Soft Tissue Root Coverage Procedures: A Systematic Review From the AAP Regeneration Workshop","volume":"86","author":"Chambrone L.","year":"2015","journal-title":"Journal of 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