{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:46:04Z","timestamp":1791989164991,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>\n                    <jats:styled-content style=\"fixed-case\">ABSTRACT<\/jats:styled-content>\n                  <\/jats:title>\n                  <jats:p>Diagnostic tests are central to medical care, and their evaluation remains methodologically challenging. This methodological article outlines the key measures used to quantify diagnostic accuracy, highlights common sources of bias and variability in diagnostic accuracy studies, and discusses how the clinical effectiveness of medical tests can be evaluated. Examples of diagnostic tests from various fields, including clinical, radiographic, biomarker, and emerging AI\u2010based approaches, are discussed. We argue that diagnostic accuracy represents only the first step in test evaluation and must be complemented by assessments of feasibility, clinical impact, and patient\u2010centered outcomes.<\/jats:p>","DOI":"10.1111\/jre.70128","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T12:23:53Z","timestamp":1781526233000},"page":"782-791","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond"],"prefix":"10.1111","volume":"61","author":[{"given":"Nancy","family":"Vegas","sequence":"first","affiliation":[{"name":"Department of General Pediatrics and Pediatric Infectious Diseases APHP, Necker\u2010Enfants Malades Hospital  Paris France"},{"name":"Paris Cit\u00e9 University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3056-3624","authenticated-orcid":false,"given":"Lisa","family":"Friedlander","sequence":"additional","affiliation":[{"name":"Paris Cit\u00e9 University  Paris France"},{"name":"Department of Maxillofacial and Plastic Surgery APHP, Necker\u2010Enfants Malades Hospital  Paris France"},{"name":"Imagine Institute  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3572-8985","authenticated-orcid":false,"given":"J\u00e9r\u00e9mie F.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics and Pediatric Infectious Diseases APHP, Necker\u2010Enfants Malades Hospital  Paris France"},{"name":"Paris Cit\u00e9 University  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9 and Universit\u00e9 Sorbonne Paris Nord INSERM, INRAE, Centre for Research in Epidemiology and Statistics  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119756194.ch3"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102016\u2010012799"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2005.048595"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13545"},{"key":"e_1_2_15_6_1","volume-title":"Consolidated Guidelines on Differentiated HIV Testing Services [Internet]","year":"2024"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051x.1991.tb02303.x"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.329.7458.168"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096\u2010016\u20102800\u2010z"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.14149"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.15389"},{"issue":"5","key":"e_1_2_15_12_1","first-page":"313","article-title":"A Closer Look at Diagnosis in Clinical Dental Practice: Part 2. 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