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The MINI International Psychiatric Interview was used to determine whether participants met DSM\u2010IV criteria for ASPD and Axis\u2010I psychological comorbidities (eg, major depressive disorder, posttraumatic stress disorder, generalized anxiety disorder). Participants were also tested for herpes simplex 2, hepatitis C, and HIV. Multivariate generalized linear mixed modeling was used to determine the association between ASPD and risk behaviors, substance use, and social network characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Approximately one\u2010third (31%) of participants met DSM\u2010IV criteria for ASPD. In multivariate analysis, distrust and conflict within an individual's social networks, as well as past 30\u2010day use of heroin and crack, male gender, younger age, lesser education, heterosexual orientation, and comorbid MDD were associated with meeting diagnostic criteria for ASPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Participants meeting criteria for ASPD were more likely to report recent heroin and crack use, which are far less common drugs of abuse in this population in which the predominant drug of abuse is prescription opioids. Greater discord within relationships was also identified among those with ASPD symptomatology. Given the elevated risk for blood\u2010borne infection (eg, HIV) and other negative social and health consequences conferred by this high\u2010risk subgroup, exploration of tailored network\u2010based interventions with mental health assessment is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jrh.12184","type":"journal-article","created":{"date-parts":[[2016,5,12]],"date-time":"2016-05-12T13:07:13Z","timestamp":1463058433000},"page":"198-207","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Individual and Network Correlates of Antisocial Personality Disorder Among Rural Nonmedical Prescription Opioid Users"],"prefix":"10.1111","volume":"33","author":[{"given":"Rachel V.","family":"Smith","sequence":"first","affiliation":[{"name":"Center on Drug and Alcohol Research, Department of Behavioral Science University of Kentucky College of Medicine  Lexington Kentucky"},{"name":"Department of Epidemiology University 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