{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:49:50Z","timestamp":1781585390535,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T00:00:00Z","timestamp":1365379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:bold>To evaluate left ventricular geometry in dogs with various stages of myxomatous mitral valve disease.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:bold>Ninety\u2010seven dogs with myxomatous mitral valve disease classified by the International Small Animal Cardiac Health Council system and 20 weight\u2010 and age\u2010matched healthy dogs. Left ventricular long\u2010axis to short\u2010axis ratio, sphericity index in end\u2010diastole and end\u2010systole, left ventricular wall thickness to internal dimension ratio and relative wall thickness were assessed.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:bold>The diastolic sphericity index was lower in classes Ib,<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>than in healthy dogs (P=0\u00b7003, P&lt;0\u00b7001 and P&lt;0\u00b7001) and was also lower in class<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>than in classes Ia, Ib and class<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>dogs (P&lt;0\u00b7001, P&lt;0\u00b7001 and P=0\u00b7002). The relative wall thickness was lower in classes<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>than in class Ia (P=0\u00b7003 and P&lt;0\u00b7001), class Ib (P=0\u00b7004 and P&lt;0\u00b7001), and healthy dogs (P&lt;0\u00b7001 and P&lt;0\u00b7001) and was also lower in class<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>than in class<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>(P=0\u00b7005).<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p><jats:bold>Sphericity index and relative wall thickness are simple methods for assessing left ventricular geometry using two\u2010dimensional echocardiography that may be useful in myxomatous mitral valve disease dogs as part of risk stratification.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12058","type":"journal-article","created":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T09:11:50Z","timestamp":1365412310000},"page":"234-239","source":"Crossref","is-referenced-by-count":11,"title":["Left ventricular geometrical differences in dogs with various stages of myxomatous mitral valve disease"],"prefix":"10.1111","volume":"54","author":[{"given":"R.","family":"Suzuki","sequence":"first","affiliation":[{"name":"Division of Veterinary Internal Medicine, Department of Veterinary Science, Faculty of Veterinary Medicine Nippon Veterinary and Life Science University 1\u20107\u20101 Kyonan\u2010cho Musashino\u2010shi Tokyo 180\u20108602 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Division of Veterinary Internal Medicine, Department of Veterinary Science, Faculty of Veterinary Medicine Nippon Veterinary and 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