{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:27:20Z","timestamp":1761676040332},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,5,10]],"date-time":"2013-05-10T00:00:00Z","timestamp":1368144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:bold>Blood gas analysis is a well\u2010recognized method to monitor pulmonary function, blood oxygenation, ventilation and acid\u2013base status during general anaesthesia. The aim of this study was to report blood gas analysis results in pet rabbits (<jats:italic>Oryctolagus cuniculus<\/jats:italic>) obtained during general anaesthesia using a portable clinical analyser.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:bold>Thirty\u2010two rabbits were premedicated with 0\u00b72 <jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>\/kg fentanyl and fluanisone. Anaesthesia was induced with 0\u00b72 mg\/kg midazolam and maintained with 2% isoflurane in oxygen via endotracheal tube. Arterial blood samples were taken from the central ear artery 10 minutes after induction of anaesthesia.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:bold>Respiratory acidaemia was observed during anaesthesia. Mean \u00b1sd (range) arterial blood <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content> was 7\u00b733 \u00b10\u00b708 (7\u00b715 to 7\u00b748). <jats:styled-content style=\"fixed-case\">PaCO<jats:sub>2<\/jats:sub><\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PaO<jats:sub>2<\/jats:sub><\/jats:styled-content> were, respectively, 55\u00b702 \u00b110\u00b75 (37\u00b77 to 92\u00b71) <jats:styled-content style=\"fixed-case\">mmHg<\/jats:styled-content> and 370\u00b70 \u00b1120\u00b75 (67 to 561) <jats:styled-content style=\"fixed-case\">mmHg<\/jats:styled-content>. Base excess was 2\u00b78 \u00b13\u00b76 (\u22123 to 11) mmol\/L, <jats:styled-content style=\"fixed-case\">HCO<jats:sub>3<\/jats:sub><\/jats:styled-content> was 28\u00b773 \u00b13\u00b707 (23\u00b77 to 35\u00b74) mmol\/L and <jats:styled-content style=\"fixed-case\">TCO<jats:sub>2<\/jats:sub><\/jats:styled-content> was 30\u00b74 \u00b13\u00b72 (25 to 37) mmol\/L. None of the rabbits developed haematoma during arterial blood collection or ischaemia of the pinna during the hospitalization period.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p><jats:bold>Arterial blood gas analysis is a safe and easy to perform diagnostic technique that can contribute to improved safety of rabbit anaesthesia, by providing information on the respiratory and metabolic status of the patient.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12081","type":"journal-article","created":{"date-parts":[[2013,5,10]],"date-time":"2013-05-10T05:38:43Z","timestamp":1368164323000},"page":"343-346","source":"Crossref","is-referenced-by-count":10,"title":["Arterial blood gas parameters in pet rabbits anaesthetized using a combination of fentanyl\u2010fluanisone\u2010midazolam\u2010isoflurane"],"prefix":"10.1111","volume":"54","author":[{"given":"L.","family":"Benato","sequence":"first","affiliation":[{"name":"Royal (Dick) School of Veterinary Studies and The Roslin Institute, Division of Veterinary Clinical Sciences The University of Edinburgh, Hospital for Small Animals, Easter Bush Veterinary Centre  Roslin Midlothian EH25 9RG Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Chesnel","sequence":"additional","affiliation":[{"name":"Royal (Dick) School of Veterinary Studies and The Roslin Institute, Division of Veterinary Clinical Sciences The University of Edinburgh, Hospital for Small Animals, Easter Bush Veterinary Centre  Roslin Midlothian EH25 9RG Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Eatwell","sequence":"additional","affiliation":[{"name":"Royal (Dick) School of Veterinary Studies and The Roslin Institute, Division of Veterinary Clinical Sciences The University of Edinburgh, Hospital for Small Animals, Easter Bush Veterinary Centre  Roslin Midlothian EH25 9RG Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Meredith","sequence":"additional","affiliation":[{"name":"Royal (Dick) School of Veterinary Studies and The Roslin Institute, Division of Veterinary Clinical Sciences The University of Edinburgh, Hospital for Small Animals, Easter Bush Veterinary Centre  Roslin Midlothian EH25 9RG Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(70)90040-X"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1258\/la.2009.009036"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1258\/002367792780745904"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2005.00169.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2008.00397.x"},{"key":"e_1_2_5_7_1","first-page":"255","article-title":"The cardiopulmonary effects of sevoflurane, isoflurane and halothane anesthesia during spontaneous or controlled ventilation in dogs","volume":"56","author":"\u00c7e\u00e7en G.","year":"2009","journal-title":"Veterinary Journal of Ankara University"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.28.1.70-75.1990"},{"key":"e_1_2_5_9_1","first-page":"156","volume-title":"Veterinary Anaesthesia, Principles to Practice","author":"Dugdale A","year":"2010"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2011.00287.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)30851-8"},{"key":"e_1_2_5_12_1","first-page":"83","volume-title":"Monitoring","author":"Heard D. 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