{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T19:58:10Z","timestamp":1788551890857,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      <jats:bold>To identify potential prognostic factors affecting outcome in septic peritonitis caused by gastrointestinal perforation in dogs and cats.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      <jats:bold>A retrospective study. Animals operated on for septic peritonitis because of gastrointestinal perforation were evaluated. Risk factors assessed included age, duration of clinical signs, recent prior abdominal surgery, recent prior anti\u2010inflammatory drug administration, placement of a closed\u2010suction drain and location of perforation.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:bold>Fifty\u2010five animals (44 dogs and 11 cats) were included. The overall mortality was 63\u00b76%. No association was found between age, duration of clinical signs or prior abdominal surgery and outcome. Animals with a history of prior anti\u2010inflammatory drugs were significantly (P=0\u00b70011) more likely to have perforation of the pylorus (73\u00b73%). No significant difference in outcome was found between animals treated with closed\u2010suction drains and those treated with primary closure or between pyloric perforation and perforation at other gastrointestinal sites.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>\n                      <jats:bold>Administration of anti\u2010inflammatory drugs in dogs and cats is a significant risk factor for pyloric perforation. Pyloric perforation was not associated with a poorer outcome than perforation at other gastrointestinal sites. Placement of a closed suction drain did not improve outcome compared to primary closure.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.12151","type":"journal-article","created":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T07:11:23Z","timestamp":1382598683000},"page":"625-629","source":"Crossref","is-referenced-by-count":30,"title":["Septic peritonitis from pyloric and non\u2010pyloric gastrointestinal perforation: prognostic factors in 44 dogs and 11 cats"],"prefix":"10.1111","volume":"54","author":[{"given":"T.","family":"Dayer","sequence":"first","affiliation":[{"name":"Department of Small Animal Surgery, Vetsuisse Faculty University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Howard","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Vetsuisse Faculty University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Spreng","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery, Vetsuisse Faculty University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,24]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"69","article-title":"Prevalence of small intestinal dehiscence and associated clinical factors: a retrospective study of 121 dogs","volume":"28","author":"Allen D. 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