{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:18:44Z","timestamp":1773011924840,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T00:00:00Z","timestamp":1391731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:p><jats:bold>A case of protothecosis causing non\u2010ambulatory paraparesis in a dog without clinical evidence of disseminated infection is described. A five\u2010year\u2010old female Labrador retriever was referred with a 10\u2010day history of progressive non\u2010ambulatory paraparesis and lumbar pain as the only physical and neurological abnormalities. Lumbar myelography revealed severe extradural spinal cord compression extending from<jats:styled-content style=\"fixed-case\">L4<\/jats:styled-content>to<jats:styled-content style=\"fixed-case\">L7<\/jats:styled-content>vertebrae, and a right hemilaminectomy was performed. Surgical findings included an adherent whitish hard ill\u2010defined mass. Cytology and biopsy results disclosed the presence of algae enclosed in a matrix of chronic inflammatory infiltrate. Culture confirmed the presence of<jats:italic>Prototheca<\/jats:italic>species. Neurological improvement occurred within a month, and the dog received antifungal treatment without evidence of clinical disseminated disease for 6 months, but died after a generalised tonic\u2013clonic seizure. Post\u2010mortem examination revealed multiple foci of inflammatory granulomatous infiltrate and algae\u2010like structures in the brain, lumbar intumescence and cauda equina.<jats:italic>Prototheca zopfii<\/jats:italic>was identified using molecular biology methods.<\/jats:bold><\/jats:p>","DOI":"10.1111\/jsap.12188","type":"journal-article","created":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T05:52:56Z","timestamp":1391752376000},"page":"283-286","source":"Crossref","is-referenced-by-count":13,"title":["Paraparesis as initial manifestation of a<i>Prototheca zopfii<\/i>infection in a dog"],"prefix":"10.1111","volume":"55","author":[{"given":"C.","family":"Font","sequence":"first","affiliation":[{"name":"Hospital ARS Veterinaria Cardedeu 3 08023 Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Mascort","sequence":"additional","affiliation":[{"name":"Hospital ARS Veterinaria Cardedeu 3 08023 Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"M\u00e1rquez","sequence":"additional","affiliation":[{"name":"Center of Animal Biotechnology and Gene Therapy (CBATEG) Universitat Aut\u00f2noma de Barcelona 08193 Bellaterra Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Esteban","sequence":"additional","affiliation":[{"name":"Microbiology and Parasitology Service Hospital Cl\u00ednic de Barcelona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Hospital ARS Veterinaria Cardedeu 3 08023 Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Durall","sequence":"additional","affiliation":[{"name":"Hospital ARS Veterinaria Cardedeu 3 08023 Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pumarola","sequence":"additional","affiliation":[{"name":"Center of Animal Biotechnology and Gene Therapy (CBATEG) Universitat Aut\u00f2noma de Barcelona 08193 Bellaterra Spain"},{"name":"Department of Animal Medicine and Surgery, Veterinary faculty Universitat Aut\u00f2noma de Barcelona 08193 Bellaterra Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Luj\u00e1n","sequence":"additional","affiliation":[{"name":"Hospital ARS Veterinaria Cardedeu 3 08023 Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,7]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2009.04.015"},{"key":"e_1_2_4_3_1","first-page":"659","volume-title":"Infectious Diseases of the Dog and Cat","author":"Greene C. 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