{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T22:15:19Z","timestamp":1769120119401,"version":"3.49.0"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T00:00:00Z","timestamp":1427760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>To evaluate endomyocardial and epimyocardial left ventricular circumferential and longitudinal peak systolic strain and strain rate in dogs with myxomatous mitral valve disease using two\u2010dimensional feature tracking imaging echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>MATERIALS AND METHODS<\/jats:title><jats:p>Epimyocardial and endomyocardial global and regional myocardial peak systolic strain and strain rate using two\u2010dimensional feature tracking imaging were evaluated in healthy dogs and those in stages<jats:styled-content style=\"fixed-case\">B1<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\">B2<\/jats:styled-content>and C of myxomatous mitral valve disease. Strain and strain rate in circumferential and longitudinal aspect were evaluated in 48 small\u2010 and medium\u2010sized dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Global endomyocardial circumferential strain and global epimyocardial circumferential strain systolic peak were lower in stage C than in stage<jats:styled-content style=\"fixed-case\">B2<\/jats:styled-content>(P\u2009=\u20090\u2009\u00b7\u200904 and P\u2009=\u20090\u2009\u00b7\u200902) and similar to healthy dogs. Endomyocardial circumferential strain rate in septal and inferior segments were lower in stage C compared to<jats:styled-content style=\"fixed-case\">B2<\/jats:styled-content>(P\u2009=\u20090\u2009\u00b7\u20090007 and P\u2009=\u20090\u2009\u00b7\u20090056), but not different from healthy dogs. There were no statistical differences in the epimyocardial circumferential strain rate, longitudinal strain and strain rate between healthy and affected dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>CLINICAL SIGNIFICANCE<\/jats:title><jats:p>Two\u2010dimensional feature tracking imaging determination of myocardial deformation in epimyocardial and endomyocardial layers allows detection of increased compensatory circumferential left ventricular myocardial systolic performance due to volume overload and absence of this response as disease advances to congestive heart failure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12347","type":"journal-article","created":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T20:12:50Z","timestamp":1427832770000},"page":"383-392","source":"Crossref","is-referenced-by-count":10,"title":["Systolic cardiac function assessment by feature tracking echocardiography in dogs with myxomatous mitral valve disease"],"prefix":"10.1111","volume":"56","author":[{"given":"M. M.","family":"Mantovani","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine Federal University of Lavras Lavras 37200\u2010000 MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A. L.","family":"Muzzi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Federal University of Lavras Lavras 37200\u2010000 MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. G.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Veterinary Cardiology, Naya Specialties S\u00e3o Paulo 09560\u2010500 SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J.","family":"Yamato","sequence":"additional","affiliation":[{"name":"Veterinary Cardiology, Naya Specialties S\u00e3o Paulo 09560\u2010500 SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. C.","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Federal University of Lavras Lavras 37200\u2010000 MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. F.","family":"Reis","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Federal University of Lavras Lavras 37200\u2010000 MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. A. L.","family":"Muzzi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Federal University of Lavras Lavras 37200\u2010000 MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. C.","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Faculty of Mathematics Federal University of Uberl\u00e2ndia Uberl\u00e2ndia MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,31]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.040"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0392.x"},{"key":"e_1_2_5_4_1","first-page":"49","article-title":"Layer\u2010specific strain analysis: investigation of regional deformations in a rat model of acute versus chronic myocardial infarction","volume":"303","author":"Bachner\u2010Hinenzon N.","year":"2012","journal-title":"American Journal of Physiology"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2001.110786"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2011.01386.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2009.00803.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(98)50126-X"},{"key":"e_1_2_5_9_1","first-page":"105","volume-title":"Manual of Veterinary Echocardiography","author":"Boon J. A.","year":"2011"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2010.03.008"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.03.108"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-7-8"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep214"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2013.02.006"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2011.11.005"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2006.11.002"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.09.007"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1760-2734(06)70033-9"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-10-0844"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12075"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960241106"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2002.tb01051.x"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.05.002"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.03.024"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2012.01.001"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.10.004"},{"key":"e_1_2_5_27_1","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.2460\/ajvr.1984.45.10.2015","article-title":"Normal values of the canine M\u2010mode echocardiogram","volume":"45","author":"Lombard C. W.","year":"1984","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep226"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.07.005"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jen230"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2013.01.009"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0592.x"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12293"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2012.09.001"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12058"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12024"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1993.tb01015.x"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0403.x"},{"key":"e_1_2_5_39_1","first-page":"1158","article-title":"Validation of a new method to quantify regional myocardial function","volume":"102","author":"Urheim S.","year":"2000","journal-title":"Myocardial strain by Doppler echocardiography. Circulation"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.2459\/01.JCM.0000253826.44234.09"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00025.2002"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0575.x"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12114"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2012.01017.x"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsap.12347","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsap.12347","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.12347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T19:47:19Z","timestamp":1747856839000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.12347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,31]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1111\/jsap.12347"],"URL":"https:\/\/doi.org\/10.1111\/jsap.12347","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,31]]}}}