{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T11:37:00Z","timestamp":1792237020660,"version":"4.4.0"},"reference-count":68,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T00:00:00Z","timestamp":1444608000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Hyperlipidaemia refers to an increased concentration of lipids in the blood. Hyperlipidaemia is common in dogs and has recently emerged as an important clinical condition that requires a systematic diagnostic approach and appropriate treatment. Hyperlipidaemia can be either primary or secondary to other diseases. Secondary hyperlipidaemia is the most common form in dogs, and it can be a result of endocrine disorders, pancreatitis, cholestasis, protein\u2010losing nephropathy, obesity, as well as other conditions and the use of certain drugs. Primary hyperlipidaemia is less common in the general canine population but it can be very common within certain breeds. Hypertriglyceridaemia of Miniature Schnauzers is the most common form of primary hyperlipidaemia in dogs but other breeds are also affected. Possible complications of hyperlipidaemia in dogs include pancreatitis, liver disease, atherosclerosis, ocular disease and seizures. Management of primary hyperlipidaemia in dogs is achieved by administration of ultra low\u2010fat diets with or without the administration of lipid lowering drugs such as omega\u20103 fatty acids, fibrates, niacin and statins.<\/jats:p>","DOI":"10.1111\/jsap.12396","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T00:44:13Z","timestamp":1444697053000},"page":"595-605","source":"Crossref","is-referenced-by-count":94,"title":["Canine hyperlipidaemia"],"prefix":"10.1111","volume":"56","author":[{"given":"P. G.","family":"Xenoulis","sequence":"first","affiliation":[{"name":"Clinic of Medicine, Faculty of Veterinary Medicine University of Thessally Trikalon 224, Karditsa 43100, Greece and Animal Medical Center of Athens, Mesogeion 267 15451 Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Steiner","sequence":"additional","affiliation":[{"name":"Clinic of Medicine, Faculty of Veterinary Medicine University of Thessally Trikalon 224, Karditsa 43100, Greece and Animal Medical Center of Athens, Mesogeion 267 15451 Athens Greece"},{"name":"Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Texas A&amp;M University College Station TX 77843 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.231.1.79"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2003.50110"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1993.tb03523.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.2460\/ajvr.1976.37.11.1355","article-title":"Normal canine lipid profiles and effects of experimentally induced pancreatitis and hepatic necrosis on lipids","volume":"37","author":"Bass V. D.","year":"1976","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.2460\/javma.1995.206.11.1684","article-title":"Evaluation and dietary considerations in idiopathic hyperlipidemia in dogs","volume":"206","author":"Bauer J. E.","year":"1995","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.1999.00846.x"},{"key":"e_1_2_10_8_1","first-page":"11","article-title":"Seizures associated with hyperlipoproteinemia in a Miniature Schnauzer","volume":"17","author":"Bodkin K.","year":"1992","journal-title":"Canine Practice"},{"key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2460\/javma.1987.190.01.81","article-title":"Clinicopathological, renal immunofluorescent, and light microscopic features of glomerulonephritis in the dog \u2013 41 cases (1975\u20131985)","volume":"190","author":"Center S. A.","year":"1987","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.57.595"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.60.413"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.1995.10718494"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00246.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-32-4-313"},{"key":"e_1_2_10_15_1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2460\/javma.1993.203.05.673","article-title":"Risk factors associated with acute pancreatitis in dogs: 101 cases (1985\u20131990)","volume":"203","author":"Cook A. K.","year":"1993","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1993.tb03522.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(77)90275-3"},{"key":"e_1_2_10_18_1","first-page":"768","article-title":"Therapy of canine hyperlipidemia with bezafibrate","volume":"27","author":"De Marco V.","year":"2013","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_10_19_1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2460\/javma.1989.195.03.358","article-title":"Clinicopathologic findings in dogs with renal amyloidosis \u2013 59 cases (1976\u20131986)","volume":"195","author":"DiBartola S. P.","year":"1989","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_20_1","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2460\/javma.1990.197.04.483","article-title":"Familial renal amyloidosis in Chinese Shar\u2010Pei dogs","volume":"197","author":"DiBartola S. P.","year":"1990","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.145.17.481"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(97)90014-X"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.72.2.161"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2008.12.008"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1993.tb03520.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2003.tb02469.x"},{"key":"e_1_2_10_27_1","first-page":"665","article-title":"Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in dogs with fatal acute pancreatitis: 70 cases (1986\u20131995)","volume":"213","author":"Hess R. S.","year":"1998","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-35-3-200"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00244.x"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2005.66.81"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(05)80126-4"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)02338-4"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.233.8.1270"},{"key":"e_1_2_10_34_1","first-page":"325","article-title":"Effect of dietary fish oil and vitamin E supplementation on hematologic and serum biochemical analytes and oxidative status in young dogs","volume":"6","author":"LeBlanc C. J.","year":"2005","journal-title":"Veterinary Therapeutics"},{"key":"e_1_2_10_35_1","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.2460\/javma.1979.174.11.1211","article-title":"Canine hyperadrenocorticism \u2010 pretreatment clinical and laboratory evaluation of 117 cases","volume":"174","author":"Ling G. V.","year":"1979","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2000.tb01502.x"},{"key":"e_1_2_10_37_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2460\/javma.1986.189.02.227","article-title":"Clinical and pathological findings in dogs with atherosclerosis \u2013 21 cases (1970\u20131983)","volume":"189","author":"Liu S. K.","year":"1986","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_38_1","first-page":"205","article-title":"Canine hyperlipoproteinemia and atherosclerosis \u2013 accumulation of lipid by aortic medial cells in vivo and in vitro","volume":"87","author":"Mahley R. W.","year":"1977","journal-title":"American Journal of Pathology"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2009.12.003"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(92)90115-P"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1994.tb03198.x"},{"key":"e_1_2_10_42_1","doi-asserted-by":"crossref","first-page":"761","DOI":"10.2460\/javma.1994.204.05.761","article-title":"Hypothyroidism in dogs: 66 cases (1987\u20131992)","volume":"204","author":"Panciera D. L.","year":"1994","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-0279(77)50063-9"},{"key":"e_1_2_10_44_1","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.2460\/javma.1975.166.11.1087","article-title":"Idiopathic hyperlipoproteinemia in dogs","volume":"166","author":"Rogers W. A.","year":"1975","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_45_1","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.2460\/javma.1975.166.11.1092","article-title":"Lipids and lipoproteins in normal dogs and in dogs with secondary hyperlipoproteinemia","volume":"166","author":"Rogers W. A.","year":"1975","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.62.1297"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2840-11-125"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-33-6-544"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-009-0012-z"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb01954.x"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(77)90287-9"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5288(93)90015-8"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.204990"},{"key":"e_1_2_10_54_1","first-page":"292","article-title":"Evaluation of hyperlipidemias in dogs and cats","volume":"7","author":"Whitney M. S.","year":"1992","journal-title":"Seminars in Veterinary Medicine and Surgery (Small Animal)"},{"key":"e_1_2_10_55_1","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.2460\/ajvr.1987.48.10.1492","article-title":"Effects of acute pancreatitis on circulating lipids in dogs","volume":"48","author":"Whitney M. S.","year":"1987","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1993.tb01016.x"},{"key":"e_1_2_10_57_1","first-page":"381","volume-title":"Small Animal Gastroenterology","author":"Williams D. A.","year":"1996"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.2337\/diab.35.8.933"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2008.10.011"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb01942.x"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.1.63"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.5326\/0460229"},{"key":"e_1_2_10_63_1","first-page":"1488","article-title":"Serum triglyceride and cholesterol concentrations and lipoprotein profiles in dogs with naturally occurring pancreatitis and healthy control dogs","volume":"25","author":"Xenoulis P. G.","year":"2011","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.238.8.1011"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0644.x"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0644.x"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-9-47"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2007.00391.x"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2007.00555.x"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsap.12396","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsap.12396","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.12396","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:27:36Z","timestamp":1748651256000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.12396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":68,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/jsap.12396"],"URL":"https:\/\/doi.org\/10.1111\/jsap.12396","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}