{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:34:16Z","timestamp":1758962056131},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>The objective of this study was to compare results obtained by ZnSO<jats:sub>4<\/jats:sub> Flotation and SNAP <jats:sup>\u00ae<\/jats:sup>Giardia to those generated by the new point\u2010of\u2010care tests Single and Triple Rapid.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Prospective study evaluating 51 canine faecal samples submitted at a reference laboratory for the presence of <jats:italic>Giardia<\/jats:italic> spp. Kappa statistics, specificity, sensitivity, positive predictive value (PPV) and negative predictive value (NPV) were calculated by comparing the new tests to the combined results of ZnSO<jats:sub>4<\/jats:sub> and SNAP tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>There was fair (Single Rapid, j=0\u00b7434) to good (Triple Rapid, j =0\u00b7797) agreement with the reference tests. At this study's prevalence (59 to 61%), specificities and PPV were high (1\u00b700) with both Rapid tests, but sensitivities and NPV were lower for the Single than for the Triple (0\u00b748 <jats:italic>vs<\/jats:italic> 0\u00b783 and 0\u00b755 <jats:italic>vs<\/jats:italic> 0\u00b780) tests. At lower prevalence rates, both tests exhibited a high PPV (1\u00b700), but the NPV were higher with the Triple (0\u00b796 to 0\u00b799) than the Single (0\u00b788 to 0\u00b796) Rapid test.<\/jats:p><\/jats:sec><jats:sec><jats:title>CLINICAL SIGNIFICANCE<\/jats:title><jats:p>Both tests exhibited excellent PPV values at all prevalence rates but an excellent NPV only at low prevalence. As the prevalence is likely to be low (&lt;15%) in clinical settings, we propose that these tests may be helpful in the in\u2010house diagnosis of <jats:italic>Giardia<\/jats:italic> spp infection. However, they exhibit lower sensitivity than the combined sensitivity of ZnSO<jats:sub>4<\/jats:sub> and SNAP tests, particularly in high prevalence settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12475","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T04:46:45Z","timestamp":1464842805000},"page":"318-322","source":"Crossref","is-referenced-by-count":8,"title":["Diagnostic accuracy of two point\u2010of\u2010care kits for the diagnosis of <i>Giardia<\/i> species infection in dogs"],"prefix":"10.1111","volume":"57","author":[{"given":"M.","family":"Costa","sequence":"first","affiliation":[{"name":"Diagnostic Laboratories, Langford Veterinary Services, School of Veterinary Science University of Bristol  Bristol Langford BS405DU"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Clarke","sequence":"additional","affiliation":[{"name":"Diagnostic Laboratories, Langford Veterinary Services, School of Veterinary Science University of Bristol  Bristol Langford BS405DU"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Diagnostic Laboratories, Langford Veterinary Services, School of Veterinary Science University of Bristol  Bristol Langford BS405DU"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Papasouliotis","sequence":"additional","affiliation":[{"name":"Diagnostic Laboratories, Langford Veterinary Services, School of Veterinary Science University of Bristol  Bristol Langford BS405DU"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2010.02.005"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1865-1682.2007.01005.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-012-2909-7"},{"key":"e_1_2_5_5_1","first-page":"410","article-title":"Comparison of conventional coproscopical methods and commercial coproantigen ELISA kits for the detection of Giardia and Cryptosporidium infections in dogs and cats","volume":"117","author":"Cirak V. 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