{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:28:16Z","timestamp":1788791296982,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>To determine the prevalence of pectinate ligament dysplasia in a large group of Welsh springer spaniels; to investigate associations between pectinate ligament dysplasia and age, sex and intraocular pressure and between intraocular pressure and age and sex; and to investigate progression of pectinate ligament dysplasia in individual dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>In a prospective study, gonioscopy was performed in both eyes of 227 Welsh springer spaniels and intraocular pressure measured by rebound tonometry. Eyes were classified as \u201cunaffected\u201d if 0% of the iridocorneal angle was affected with pectinate ligament dysplasia (grade 0), \u201cmildly affected\u201d if &lt;20% was affected (grade 1), \u201cmoderately affected\u201d if 20 to 90% was affected (grade 2) and \u201cseverely affected\u201d if &gt;90% was affected (grade 3). In a retrospective study, progression of pectinate ligament dysplasia over time was investigated for 65 dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>One hundred and thirty\u2010nine of 227 dogs (61\u00b72%) were affected by pectinate ligament dysplasia (grades 1 to 3) and 82\/227 (36\u00b72%) were moderately or severely affected. There was a significant association between pectinate ligament dysplasia and age. There were no associations between pectinate ligament dysplasia and intraocular pressure or pectinate ligament dysplasia and sex. Thirty\u2010five of 65 dogs (53\u00b78%) demonstrated progression of pectinate ligament dysplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>CLINICAL SIGNIFICANCE<\/jats:title><jats:p>Prevalence of pectinate ligament dysplasia was high despite widespread screening and selection against the condition. Our data indicate that gonioscopic features of pectinate ligament dysplasia can progress in the Welsh springer spaniel. Dogs deemed unaffected at an early age may subsequently be diagnosed with pectinate ligament dysplasia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12497","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T04:50:02Z","timestamp":1464843002000},"page":"416-421","source":"Crossref","is-referenced-by-count":13,"title":["Prevalence and progression of pectinate ligament dysplasia in the Welsh springer spaniel"],"prefix":"10.1111","volume":"57","author":[{"given":"J. A. C.","family":"Oliver","sequence":"first","affiliation":[{"name":"Centre for Preventive Medicine Animal Health Trust Lanwades Park Newmarket Suffolk CB8 7UU"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ekiri","sequence":"additional","affiliation":[{"name":"Centre for Preventive Medicine Animal Health Trust Lanwades Park Newmarket Suffolk CB8 7UU"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. S.","family":"Mellersh","sequence":"additional","affiliation":[{"name":"Centre for Preventive Medicine Animal Health Trust Lanwades Park Newmarket Suffolk CB8 7UU"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1977.tb05831.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2002.00213.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1988.tb02276.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.2460\/ajvr.1991.52.11.1875","article-title":"Correlation of morphologic features of the iridocorneal angle to intraocular pressure in Samoyeds","volume":"52","author":"Ekesten B.","year":"1991","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_6_1","first-page":"37","article-title":"Age\u2010related changes in intraocular pressure and iridocorneal angle in Samoyeds","volume":"2","author":"Ekesten B.","year":"1992","journal-title":"Progress in Veterinary and Comparative Ophthalmology"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop\/12311"},{"key":"e_1_2_6_8_1","first-page":"768","volume-title":"Veterinary Ophthalmology","author":"Gelatt K. 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