{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:40:07Z","timestamp":1790912407918,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T00:00:00Z","timestamp":1509408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the utility of an in\u2010practice test kit to detect protective serum antibody against canine distemper virus, canine adenovirus and canine parvovirus type 2 in a sample of the UK dog population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Serum samples from 486 dogs, last vaccinated between less than 1\u2009month and 124\u2009months previously, were tested with the VacciCheck\u2122 test kit for protective antibodies against distemper, adenovirus and parvovirus type 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A high proportion of the dogs tested (93\u00b76%) had protective antibody against all three of the core vaccine antigens: 95\u00b77% of the dogs were seropositive against canine distemper virus, 97\u00b73% against canine adenovirus and 98\u00b75% against canine parvovirus type 2. The small number of dogs that were seronegative for one or more of the antigens (<jats:italic>n<\/jats:italic>\u2009=\u200931) may have had waning of previous serum antibody or may have been rare genetic non\u2010responders to that specific antigen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>UK veterinarians can be reassured that triennial revaccination of adult dogs with core vaccines provides long\u2010lived protective immunity. In\u2010practice serological test kits are a valuable tool for informing decision\u2010making about canine core revaccination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12775","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T13:55:02Z","timestamp":1509458102000},"page":"27-31","source":"Crossref","is-referenced-by-count":20,"title":["Long\u2010lived immunity to canine core vaccine antigens in UK dogs as assessed by an in\u2010practice test kit"],"prefix":"10.1111","volume":"59","author":[{"given":"R.","family":"Killey","sequence":"first","affiliation":[{"name":"Moreton Morrell College Moreton Morrell Warwickshire CV35 9BL UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Mynors","sequence":"additional","affiliation":[{"name":"Moreton Morrell College Moreton Morrell Warwickshire CV35 9BL UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Pearce","sequence":"additional","affiliation":[{"name":"Moreton Morrell College Moreton Morrell Warwickshire CV35 9BL UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Nell","sequence":"additional","affiliation":[{"name":"Medivet Watford Hertfordshire WD24 7UY UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Prentis","sequence":"additional","affiliation":[{"name":"Hyde Park Veterinary Centre London W2 2AE UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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