{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T19:20:34Z","timestamp":1783538434419,"version":"3.55.0"},"reference-count":55,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T00:00:00Z","timestamp":1540771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"NIH National Center for Advancing Translational Sciences","doi-asserted-by":"crossref","award":["UL1TR002373"],"award-info":[{"award-number":["UL1TR002373"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To assess the prevalence of antibodies to\n                      <jats:italic>Toxoplasma gondii<\/jats:italic>\n                      and\n                      <jats:italic>Neospora caninum<\/jats:italic>\n                      in a population of dogs with a diagnosis of suspected inflammatory meningoencephalitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Medical records of three referral centres were reviewed from 2008 to 2016 to identify a cohort of dogs diagnosed and treated for suspected inflammatory meningoencephalitis after testing for evidence of exposure to these pathogens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In our sample of 400 dogs the prevalence for exposure (IgG&gt;1:50) to\n                      <jats:italic>Toxoplasma gondii<\/jats:italic>\n                      was 8\/201 (3\u221998%). Active infection (IgG titre &gt;1:400 or\/and an IgM titre &gt;1:64 and\/or positive PCR in CSF) was suspected in 1\/400 (0\u221925%). The prevalence for exposure [Indirect fluorescent antibody (IFA) titre &gt;1:50] and active infection (IFA titres \u2265\u20d21:400 and\/or positive PCR in CSF) with\n                      <jats:italic>Neospora caninum<\/jats:italic>\n                      were 14\/201 (6\u221996%) and 9\/400 (2\u221925%), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>In view of the low prevalence of protozoan infections, the risk associated with starting immunosuppressive medication in dogs with evidence of inflammatory meningitis or encephalitis in the UK appears low.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.12937","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T09:10:29Z","timestamp":1540804229000},"page":"44-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Serological prevalence of toxoplasmosis and neosporosis in dogs diagnosed with suspected meningoencephalitis in the UK"],"prefix":"10.1111","volume":"60","author":[{"given":"A. M.","family":"Coelho","sequence":"first","affiliation":[{"name":"Dick White Referrals (DWR) Veterinary Specialist Centre Cambridge CB8 0UH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Cherubini","sequence":"additional","affiliation":[{"name":"Dick White Referrals (DWR) Veterinary Specialist Centre Cambridge CB8 0UH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"De Stefani","sequence":"additional","affiliation":[{"name":"Dick White Referrals (DWR) Veterinary Specialist Centre Cambridge CB8 0UH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Negrin","sequence":"additional","affiliation":[{"name":"Dick White Referrals (DWR) Veterinary Specialist Centre Cambridge CB8 0UH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gutierrez\u2010Quintana","sequence":"additional","affiliation":[{"name":"College of Medicine, Veterinary and Life Sciences, School of Veterinary Medicine University of Glasgow Glasgow G61 1QH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bersan","sequence":"additional","affiliation":[{"name":"School of Veterinary Science, Small Animal Teaching Hospital University of Liverpool CH64 7TE, Neston, Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Guevar","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of Wisconsin\u2010Madison Madison Wisconsin 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,29]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"678","article-title":"Granulomatous meningoenceph\u2010 alomyelitis in dogs","volume":"29","author":"Adamo P. 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