{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:18:58Z","timestamp":1761718738896},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T00:00:00Z","timestamp":1542153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine whether artificial urethral sphincter filling volume is proportional to peak pressure exerted on the urethra.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Urethral pressure profilometry was performed in five female, medium\u2010sized, mixed\u2010breed canine cadavers following artificial urethral sphincter placement. Maximum urethral pressure was recorded following sequential incremental inflation of 0.15\u2009mL and compared to baseline pressure and between dogs using two\u2010way analysis of variance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Artificial urethral sphincter placement in cadavers was associated with an increase in urethral pressure, which was significantly correlated with inflation volume. The correlation was non\u2010linear and demonstrated considerable individual variation. Maximum urethral pressures after artificial urethral sphincter placement exceeded those reported in conscious continent dogs within a narrow volume range, in which a 0.15\u2009mL infusion more than doubled maximal urethral pressures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>Rapid increases in urethral pressure from the artificial urethral sphincter over a small range of filling volumes (0.15\u2009mL increments) might explain why some clinical cases can become suddenly dysuric following incremental inflations. We suggest that smaller increments of filling (0.05\u00a0to 0.1\u00a0mL) may achieve finer pressure control.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.12961","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T12:53:06Z","timestamp":1542286386000},"page":"313-318","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Canine urethral sphincter pressure profile under incremental inflation of an artificial cuff: a cadaver study"],"prefix":"10.1111","volume":"60","author":[{"given":"E. J.","family":"Milodowski","sequence":"first","affiliation":[{"name":"Bristol Veterinary School, Faculty of Health Sciences University of Bristol  Bristol BS8 1TD UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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