{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:20:44Z","timestamp":1784938844305,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T00:00:00Z","timestamp":1562889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the prevalence of canine parainfluenza virus, canine adenovirus type 2, canine distemper virus, canine respiratory coronavirus and influenza virus A infections in: (1) privately\u2010owned or, (2) kennelled dogs showing signs consistent with canine infectious respiratory disease and, (3) clinically healthy dogs in Vienna, Austria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Prospectively, nasal and tonsillar swabs from 214 dogs affected with infectious respiratory disease, and 50 healthy control dogs were tested for nucleic acids specific to the various viral infections. Concurrent bronchoalveolar lavage fluid from 31 dogs with chronic respiratory disease was investigated for the same viral pathogens. Additionally, anti\u2010canine respiratory coronavirus antibody concentrations were measured in paired blood samples from 30 acutely diseased dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Canine respiratory coronavirus (7.5%) and canine parainfluenza virus (6.5%) were the most commonly detected viruses in samples from the upper airways of dogs with respiratory infections. Serological results showed a significant seroconversion in response to coronavirus in 50% of the examined cases. None of the samples was positive for influenza virus A\u2010specific nucleic acid. Canine coronavirus\u2010specific nucleic acid was detected in 4.0% of healthy dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>Canine coronavirus should be considered as a clinically relevant cause of infectious respiratory disease in crowded dog populations. For sample collection, the nasal mucosa can be recommended as the favoured site. Analysis of paired serum samples aids verification of canine coronavirus infection in respiratory disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13051","type":"journal-article","created":{"date-parts":[[2019,7,13]],"date-time":"2019-07-13T04:58:31Z","timestamp":1562993911000},"page":"594-600","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Detection of selected viral pathogens in dogs with canine infectious respiratory disease in Austria"],"prefix":"10.1111","volume":"60","author":[{"given":"A.","family":"Hiebl","sequence":"first","affiliation":[{"name":"Clinic for Small Animal Internal Medicine, Department for Companion Animals and Horses University of Veterinary Medicine Vienna  Vienna 1210 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Auer","sequence":"additional","affiliation":[{"name":"Institute of Virology University of Veterinary Medicine Vienna  Vienna 1210 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bagrinovschi","sequence":"additional","affiliation":[{"name":"Institute of Virology University of Veterinary Medicine Vienna  Vienna 1210 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Stejskal","sequence":"additional","affiliation":[{"name":"Kleintierklinik Breitensee Wien  Vienna 1140 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Hirt","sequence":"additional","affiliation":[{"name":"Clinic for Small Animal Internal Medicine, Department for Companion Animals and Horses University of Veterinary Medicine Vienna  Vienna 1210 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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