{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:58:27Z","timestamp":1787065107712,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,4,22]],"date-time":"2020-04-22T00:00:00Z","timestamp":1587513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To summarise the clinical presentation and outcomes in a series of miniature schnauzers diagnosed with histiocytic sarcoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Retrospective review of medical records of miniature schnauzers diagnosed with histiocytic sarcoma between 2008 and 2019 at two referral centres in the UK. Signalment, clinical signs at initial presentation, imaging results and clinico\u2010 and histopathological findings, treatment type and outcome were recorded. Progression\u2010free survival and overall survival time were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty dogs were included. Twenty\u2010four of 29 dogs undergoing imaging of the thorax had lung and\/or mediastinal involvement. The median overall survival time for dogs that were not euthanased within 3\u2009days of diagnosis was 117\u2009days (range 10 to 790). Three dogs underwent surgery; 13 received treatment with lomustine as a sole therapy \u2010 with partial responses documented on imaging in five of six dogs and 11 of 13 showing clinical improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>Histiocytic sarcoma should be considered as a differential diagnosis for miniature schnauzers with pulmonary masses. Although responses to treatment were common, they were usually short\u2010lived because of the aggressive nature of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.13139","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T02:16:00Z","timestamp":1587608160000},"page":"338-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Histiocytic sarcoma in miniature schnauzers: 30 cases"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-0135","authenticated-orcid":false,"given":"K.","family":"Purzycka","sequence":"first","affiliation":[{"name":"Queen Mother Hospital for Animals Royal Veterinary College, University of London North Mymms UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. M.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Pathobiology and Population Sciences, Royal Veterinary College University of London Hatfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Elliott","sequence":"additional","affiliation":[{"name":"North Carolina State University Department of Radiation Oncology 1060 William Moore Drive, Raleigh NC 27606 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6952-8231","authenticated-orcid":false,"given":"C. R.","family":"Lamb","sequence":"additional","affiliation":[{"name":"Queen Mother Hospital for Animals Royal Veterinary College, University of London North Mymms UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. L.","family":"Priestnall","sequence":"additional","affiliation":[{"name":"Department of Pathobiology and Population Sciences, Royal Veterinary College University of London Hatfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hardas","sequence":"additional","affiliation":[{"name":"Anderson Moores Veterinary Specialists The Granary, Bunstead Barns Winchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. A.","family":"Johnston","sequence":"additional","affiliation":[{"name":"Queen Mother Hospital for Animals Royal Veterinary College, University of London North Mymms UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Rodriguez\u2010Piza","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Veterinari Gl\u00f2ries Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12154"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.1994.tb00921.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.13805"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12354"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810385153"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.39-1-66"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12252"},{"key":"e_1_2_6_9_1","first-page":"7","article-title":"Morphological distinction of histiocytic sarcoma from other tumor types in bernese mountain dogs and flat\u2010coated retrievers","volume":"32","author":"Erich S. 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