{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:13:34Z","timestamp":1785600814909,"version":"3.56.0"},"reference-count":44,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002141","name":"Public Health England","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To describe infection in companion animals with the zoonotic pathogen\n                      <jats:italic>Corynebacterium ulcerans<\/jats:italic>\n                      and to determine its prevalence in clinically\u2010affected and healthy animals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      The clinical presentation and treatment of three cases of\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      infection is described. Two studies to determine\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      prevalence rates were undertaken: (a) a prospective study of nasal samples from healthy animals, 479 dogs and 72 cats; (b) a retrospective analysis of records of nasal samples collected over a 10\u2010year period from 189 dogs and 64 cats affected by respiratory signs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Toxigenic\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      was isolated from four cats with nasal discharge while concurrent\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      and\n                      <jats:italic>mecC<\/jats:italic>\n                      methicillin\u2010resistant\n                      <jats:italic>S. aureus<\/jats:italic>\n                      infection was detected in a dog suffering from chronic nasal discharge. Clinical features were not distinctive and all cases recovered following antimicrobial treatment. Multilocus sequence typing supported a common source for isolates from the shelter cats. Carriage rates of\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      in healthy animals were 0.42% (2\/479) in dogs and 0.00% (0\/72) in cats whereas in animals with signs of upper respiratory tract infection prevalence rates were 0.53% (1\/189) in dogs and 6.25% (4\/64) in cats.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>\n                      Clinicians should be aware that dogs and cats can be infected with (or carriers of) toxigenic\n                      <jats:italic>C. ulcerans<\/jats:italic>\n                      Considering the potential zoonotic risk, assistance from medical and public health colleagues should be sought in confirmed cases.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.13185","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T01:29:53Z","timestamp":1596158993000},"page":"554-560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Toxigenic\n                    <i>Corynebacterium ulcerans<\/i>\n                    associated with upper respiratory infections in cats and dogs"],"prefix":"10.1111","volume":"61","author":[{"given":"Y.","family":"Abbott","sequence":"first","affiliation":[{"name":"Veterinary Pathobiology Section School of Veterinary Medicine, University College Dublin, Belfield, Stillorgan Road, Dublin, D04 W6F6  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Efstratiou","sequence":"additional","affiliation":[{"name":"WHO Global Reference Centre for Diphtheria and Streptococcal Infections, Public Health England, National Infection Service, 61 Colindale Avenue, London, NW9 5EQ  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Brennan","sequence":"additional","affiliation":[{"name":"National MRSA Reference Laboratory, St. James's Hospital, James's Street, Dublin 8  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hallanan","sequence":"additional","affiliation":[{"name":"Riverforest Veterinary Centre, Riverforest Court, Captain's Hill, Leixlip, Co. Kildare, W23 A5N4  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Leggett","sequence":"additional","affiliation":[{"name":"Veterinary Pathobiology Section School of Veterinary Medicine, University College Dublin, Belfield, Stillorgan Road, Dublin, D04 W6F6  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. C.","family":"Leonard","sequence":"additional","affiliation":[{"name":"Veterinary Pathobiology Section School of Veterinary Medicine, University College Dublin, Belfield, Stillorgan Road, Dublin, D04 W6F6  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. K.","family":"Markey","sequence":"additional","affiliation":[{"name":"Veterinary Pathobiology Section School of Veterinary Medicine, University College Dublin, Belfield, Stillorgan Road, Dublin, D04 W6F6  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Tuite","sequence":"additional","affiliation":[{"name":"Fairview Veterinary Hospital, 13 Fairview Strand, Dublin, D03 P27  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4862-6507","authenticated-orcid":false,"given":"N. K.","family":"Fry","sequence":"additional","affiliation":[{"name":"Vaccine Preventable Bacteria Section, Public Health England, National Infection Service, 61 Colindale Avenue, London, NW9 5EQ  UK"},{"name":"Immunisation and Countermeasures Division, Public Health England, National Infection Service, 61 Colindale Avenue, London, NW9 5EQ  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1709.110391"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03398-14"},{"key":"e_1_2_6_4_1","unstructured":"Bruker Daltonik GmbH. (2019) Bremen Germany. MBT Compass Library Revision F. MBT 8468 MSP Library Release Notes."},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638718764786"},{"key":"e_1_2_6_6_1","volume-title":"Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals","author":"Clinical Laboratory Standards Institute (CLSI)","year":"2013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1812.120664"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.9.4377-4381.2005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000382"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2009.0132"},{"key":"e_1_2_6_11_1","first-page":"250","article-title":"Laboratory guidelines for the diagnosis of infections caused by Corynebacterium diphtheriae and C. ulcerans. World Health Organization","volume":"2","author":"Efstratiou A.","year":"1999","journal-title":"Communicable Disease and Public Health"},{"key":"e_1_2_6_12_1","unstructured":"Efstratiou A.andMaple P. A. C.(1994) Manual for the laboratory diagnosis of diphtheria in the European Region Copenhagen: expanded Programme on Immunization in the European Region of World Health Organization ICP\/EPI 038(C)."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2003.130423"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.2.495-498.1997"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/47.1.27"},{"key":"e_1_2_6_16_1","unstructured":"European Centre for Disease Prevention and Control(2019). Diphtheria. In: ECDC. Annual epidemiological report for 2017. Stockholm: ECDC.https:\/\/ecdc.europa.eu\/sites\/portal\/files\/documents\/diphtheria\u2010annual\u2010epidemiological\u2010report\u20102017.pdf. Accessed August 2019."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01586186"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","unstructured":"Gower C. M. Scobie A. Fry N. K. Litt D. J. Cameron J. C. Chand M. A. Brown C. S. Collins S. White J. M. Ramsay M. E. Amirthalingam G.(2020) The changing epidemiology of diphtheria in the United Kingdom 2009 to 2017Eurosurveillance25 1900462","DOI":"10.2807\/1560-7917.ES.2020.25.11.1900462"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2016-0085"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102016\u2010218408"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.165.23.691"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-11-595"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.2477"},{"key":"e_1_2_6_24_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.7883\/yoken.JJID.2009.171","article-title":"Toxigenic Corynebacterium ulcerans isolated from the domestic dog for the first time in Japan","volume":"62","author":"Katsukawa C.","year":"2009","journal-title":"Japanese Journal of Infectious Diseases"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.034868-0"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1348-0421.12364"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02291-14"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.2807\/ese.15.43.19699-en"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14627"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.2.999-1001.2005"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2010.00568.x"},{"key":"e_1_2_6_32_1","volume-title":"Clinical Veterinary Microbiology","author":"Markey B.","year":"2013"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-014-0113-3"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2102.141160"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-017-1040-1"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2008.01986.x"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00225-X"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1099\/acmi.0.000025"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2013.11.003"},{"key":"e_1_2_6_40_1","unstructured":"Public Health England. (2015) Public health control and management of diphtheria (in England and Wales) guidelines.https:\/\/www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/416108\/Diphtheria_Guidelines_Final.pdf"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-019-01328-4"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0491.x"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.2308"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560\u20107917.ES2014.19.38.20910"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.12.24"}],"updated-by":[{"DOI":"10.1111\/jsap.13259","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T00:00:00Z","timestamp":1606867200000}}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsap.13185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsap.13185","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:22:35Z","timestamp":1772965355000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.13185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,30]]},"references-count":44,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/jsap.13185"],"URL":"https:\/\/doi.org\/10.1111\/jsap.13185","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,30]]},"assertion":[{"value":"2019-08-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}