{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:25:18Z","timestamp":1773030318599,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T00:00:00Z","timestamp":1602201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the prevalence of neoplasia detected on liver biopsy obtained at the time of splenectomy in dogs with splenic masses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Retrospective study of medical records of dogs with splenic masses from which liver biopsies were taken following splenectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Malignant splenic neoplasia was detected in 50 of 113 (44.2%) of the dogs undergoing splenectomy. Neoplastic liver disease was detected on biopsy from 1 of 40 (2.5%) dogs with a grossly normal liver and from 20 of 69 (28.9%) dogs with a grossly abnormal liver. Dogs with a grossly abnormal liver had a\u2009~\u200916 times (95% CI: 2.5\u2010170) higher chance of being diagnosed with liver neoplasia on biopsy. Haemoabdomen was also associated with an increased likelihood of liver neoplasia on biopsy at the time of splenectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>A liver biopsy taken from grossly normal liver is a low\u2010yield diagnostic test but liver biopsy is recommended following splenectomy if the liver appears abnormal at surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13202","type":"journal-article","created":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T18:46:00Z","timestamp":1602269160000},"page":"684-688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical utility of liver biopsies in dogs undergoing splenectomy"],"prefix":"10.1111","volume":"61","author":[{"given":"E.","family":"Clarke","sequence":"first","affiliation":[{"name":"Louisiana State University Veterinary Teaching Hospital Skip Bertman Drive, Baton Rouge LA 70803 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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