{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:55:47Z","timestamp":1791078947578,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T00:00:00Z","timestamp":1606435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To better characterise signalment, biologic behaviour, and treatment outcome in melanocytic tumours of the nasal planum in cats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Retrospective study in cats diagnosed with histopathologically confirmed melanocytic tumours on the nasal planum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten cats were identified with melanocytic tumours of the nasal planum. Pigmentation of the nasal planum seemed to be a predisposing factor. Seven cats were diagnosed histopathologically with a malignant melanoma, three with a benign melanocytoma. One of the cats developed a lymph node metastasis despite diagnosis of a well\u2010differentiated melanocytic neoplasia. In four cases, a pigmented mass, which was initially stable over a long time, showed a sudden rapid progression suggesting malignant transformation. Treatments included hypofractionated radiation therapy (n\u00a0=\u00a06) and surgical resection (n\u00a0=\u00a01). In three cats no further treatment was pursued. Complete (n\u00a0=\u00a03) and partial (n\u00a0=\u00a03) remissions were observed in cats treated with radiation therapy; however, all experienced tumour progression or recurrence after a short period of time. Most of the cats (n\u00a0=\u00a07) had to be euthanased due to tumour progression (median survival time: 265\u2009days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The present case series provides insights in clinical presentation and clinical outcomes of cats with melanocytic tumours of the nasal planum.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13265","type":"journal-article","created":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T08:29:39Z","timestamp":1606465779000},"page":"131-136","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Melanocytic tumours of the nasal planum in cats: 10 cases (2004\u20132019)"],"prefix":"10.1111","volume":"62","author":[{"given":"A.","family":"Reck","sequence":"first","affiliation":[{"name":"Oncology service of Hofheim Small Animal Hospital Katharina\u2010Kemmler\u2010Stra\u00dfe 7 Hofheim 65719 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kessler","sequence":"additional","affiliation":[{"name":"Oncology service of Hofheim Small Animal Hospital Katharina\u2010Kemmler\u2010Stra\u00dfe 7 Hofheim 65719 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,27]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.2460\/javma.1996.209.01.98","article-title":"Radiotherapy of oral malignant melanomas in dogs","volume":"209","author":"Blackwood L.","year":"1996","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.388"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15625355"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1995.tb02898.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2004.04015.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12170"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2000.0092"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098589102800506"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1993.tb00185.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/vetsci3010007","article-title":"Comparative aspects of canine melanoma","volume":"3","author":"Nishiya A. 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