{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:56:16Z","timestamp":1791284176412,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T00:00:00Z","timestamp":1611619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the accuracy of the lung ultrasound protocol Vet BLUE, using thoracic CT as the reference standard, for the detection of thoracic pathology in dogs and cats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Animals that had thoracic ultrasound and thoracic CT were prospectively recruited between May 2017 and September 2018. The Vet BLUE protocol was performed on animals at the time of admission by veterinarians with basic training in emergency ultrasound. A board\u2010certified radiologist, blinded to the Vet BLUE findings, reviewed the CT images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CT was abnormal in 64.5% (20\/31) animals. The number of CT sites positive for alveolar\u2010interstitial syndrome was 24.2% (60\/248). When using CT as the reference standard, detection of\u2009\u22653 B lines with thoracic ultrasound had a sensitivity of 18.33% and specificity of 98.4% for detection of site specific alveolar\u2010interstitial syndrome. The sensitivity of Vet BLUE to detect alveolar\u2010interstitial syndrome increased to 56.9% when including the presence of any B line as abnormal. Overall accuracy for detection of alveolar\u2010interstitial syndrome based on these two criteria was 79% and 73%, respectively. Vet BLUE correctly identified consolidation in 58.3% (14\/24) sites, pleural effusion in 66.6% (2\/3) cases, pneumothorax in 33.3% (1\/3) cases and intrathoracic mass in 25% (1\/4) cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The Vet BLUE protocol is a useful technique to detect alveolar\u2010interstitial syndrome and other thoracic pathology but should not be used as a sole imaging method. Detection of\u2009\u22653 B lines is highly suggestive of alveolar\u2010interstitial syndrome and warrants further diagnostics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13271","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T08:33:15Z","timestamp":1611649995000},"page":"178-186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Diagnostic accuracy of a lung ultrasound protocol (Vet <scp>BLUE<\/scp>) for detection of pleural fluid, pneumothorax and lung pathology in dogs and cats"],"prefix":"10.1111","volume":"62","author":[{"given":"L.","family":"Cole","sequence":"first","affiliation":[{"name":"Clinical Science and Services Royal Veterinary College  Hawkshead Lane, Hatfield AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pivetta","sequence":"additional","affiliation":[{"name":"Antech Imaging Services Irvine CA 92614 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Humm","sequence":"additional","affiliation":[{"name":"Clinical Science and Services Royal Veterinary College  Hawkshead Lane, Hatfield AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12968"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00291"},{"key":"e_1_2_5_4_1","unstructured":"Boysen S. Chalhoub S. Romero A.(2020) Veterinary point of care ultrasound probe orientation and position for the detection of pleural effusion in dog cadavers by novice sonographers: a pilot study. Proceedings of the European Veterinary Emergency and Critical Care Society. June 25 to 28th.http:\/\/www.evecc\u2010congress.org\/evecc_online_congress\/poster_abstracts. 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L\u00e9na G. Fr\u00e9d\u00e9ric B. et\u202fal. (2020) Comparison of thoracic point of care ultrasound and radiographic findings as well as clinical evolution and C reactive protein concentrations in dogs treated for aspiration pneumonia. Proceedings of the European Veterinary Emergency and Critical Care Society. June 25 to 28th.http:\/\/www.evecc\u2010congress.org\/evecc_online_congress\/poster_abstracts. 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