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The result was compared with the reference sequence and with the result of the sequencing of a normal dog's<jats:italic>EDA<\/jats:italic>gene. No point variant, small deletion or insertion were found in the exons and splice sites, but a transition and a transversion were found in the intron 6 and 3\u2032 UTR, respectively. The cause of the dysplasia of the affected dog in this study is neither a point variant nor a small deletion or insertion in the exons and splice sites of the<jats:italic>EDA<\/jats:italic>gene. Therefore, patients with phenotype of XLHED may have other types of variants in the<jats:italic>EDA<\/jats:italic>gene or variants in other genes of the<jats:italic>EDA<\/jats:italic>signalling pathway.<\/jats:p>","DOI":"10.1111\/jsap.13385","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T15:01:49Z","timestamp":1622646109000},"page":"1127-1130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Genetic analysis of a possible case of canine X\u2010linked ectodermal dysplasia"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2137-4901","authenticated-orcid":false,"given":"E.","family":"Moura","sequence":"first","affiliation":[{"name":"Service of Medical Genetics, Course of Veterinary Medicine, School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR) Curitiba Paran\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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