{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T13:21:33Z","timestamp":1774099293758,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T00:00:00Z","timestamp":1632873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Objectives\n<\/jats:title><jats:p>To characterise the clinical signs of suspected cerebrovascular disease in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods\n<\/jats:title><jats:p>Medical records of one hospital were searched from November 2009 to December 2016 for dogs that suffered of cerebrovascular disease. We diagnosed cerebrovascular disease based on acute onset, clinical signs and magnetic resonance imaging findings. The medical history, clinical signs, concurrent disease, area of infarction, cerebrospinal fluid results, month at onset and outcome were investigated in the cerebrovascular disease group and in a control group (dogs with brain disorders other than cerebrovascular disease).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results\n<\/jats:title><jats:p>A total of 122 CVD cases were extracted from the 5312 patients that visited during the study period. Of these 122 cases, 66 (1.2%) matched the subject selection criteria of our study and were included in the analysis. Forebrain infarction was observed in 51 of 66 cases, of which 24 (47.1%) suffered from seizures. The number of dogs diagnosed with cerebrovascular disease was disproportionately high in August (nine of 59 cases) and December (13 of 59 cases). In the outcome survey, deterioration was observed in 11 of 55 cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance\n<\/jats:title><jats:p>Seizure is an important clinical sign of cerebrovascular disease in dogs. There was a significant seasonal variation in the number of dogs diagnosed with cerebrovascular disease in Japan. Clinical features observed in this report differ from those of previous reports and highlight the need for additional research in this area.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13422","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T11:29:57Z","timestamp":1632914997000},"page":"45-51","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Characteristics and outcome of suspected cerebrovascular disease in dogs: 66 cases (2009\u20102016)"],"prefix":"10.1111","volume":"63","author":[{"given":"T.","family":"Ozawa","sequence":"first","affiliation":[{"name":"KyotoAR Veterinary Neurology Center  Kyoto 613\u20100036 Japan"},{"name":"The United Graduate School of Veterinary Science Yamaguchi University  Yamaguchi 753\u20108515 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4625-5231","authenticated-orcid":false,"given":"N.","family":"Miura","sequence":"additional","affiliation":[{"name":"Veterinary Teaching Hospital, Joint Faculty of Veterinary Medicine Kagoshima University  Kagoshima 890\u20100065 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"KyotoAR Veterinary Neurology Center  Kyoto 613\u20100036 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Uemura","sequence":"additional","affiliation":[{"name":"KyotoAR Veterinary Neurology Center  Kyoto 613\u20100036 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Neuro Vets  Kyoto 604\u20100981 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tsujio","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Anatomy, Joint Faculty of Veterinary Medicine Kagoshima University  Kagoshima 890\u20100065 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Laboratory Medicine, School of Veterinary Medicine, Faculty of Agriculture Tottori University  Tottori 680\u20108553 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7737-0075","authenticated-orcid":false,"given":"M.","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Physiology, Joint Faculty of Veterinary Medicine Kagoshima University  Kagoshima 890\u20100065 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-5480"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb03017.x"},{"key":"e_1_2_5_4_1","first-page":"212","volume-title":"Practical Guide to Canine and Feline Neurology","author":"Dewey C. 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