{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:06:41Z","timestamp":1792274801133,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021R1A2C1012058"],"award-info":[{"award-number":["2021R1A2C1012058"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>A 2\u2010year\u2010old mixed breed dog presented with a 1\u2010year history of crust and erosion on the nasal planum. Because histopathological examination revealed ruptured intraepidermal pustules and superficial dermal inflammation, the dog was diagnosed with pemphigus foliaceus. Human intravenous immunoglobulin was administered in two consecutive doses of 0.5\u00a0g\/kg\/day due to poor therapeutic response to previous immunosuppressive therapy. From Day 3 after the first dose of human intravenous immunoglobulin, tachypnoea, pale mucous membrane, haemoglobinuria and haemoglobinemia were observed, thus confirming haemolytic anaemia. Other drug\u2010induced haemolytic anaemias were excluded because no additional drugs had been administered before the haemolysis occurred. Immune\u2010mediated haemolytic anaemia was also excluded because the direct antiglobulin test was negative. Two transfusions were performed, and haemolysis was not observed from Day 4 of haemolytic anaemia onset. In conclusion, human intravenous immunoglobulin\u2010induced haemolytic anaemia should be considered in dogs that develop haemolysis following the administration of human intravenous immunoglobulin.<\/jats:p>","DOI":"10.1111\/jsap.13449","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T13:21:48Z","timestamp":1638883308000},"page":"482-485","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Suspected human intravenous immunoglobulin\u2010induced acute haemolytic anaemia in a dog"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3810-4193","authenticated-orcid":false,"given":"Y.","family":"Koo","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1372-4430","authenticated-orcid":false,"given":"T.","family":"Yun","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9816-6900","authenticated-orcid":false,"given":"Y.","family":"Chae","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-9592","authenticated-orcid":false,"given":"D.","family":"Lee","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6507-2019","authenticated-orcid":false,"given":"D.","family":"Choi","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1681-6947","authenticated-orcid":false,"given":"J.","family":"Oh","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0377-9235","authenticated-orcid":false,"given":"J.","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8882-2329","authenticated-orcid":false,"given":"H.","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine College of Veterinary Medicine, Chungbuk National University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8043-0152","authenticated-orcid":false,"given":"M. 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