{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T18:11:07Z","timestamp":1782497467470,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the prevalence of iatrogenic heart murmurs in a population of apparently healthy cats and to investigate factors that may predispose cats to iatrogenic murmurs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Apparently healthy cats presenting for routine examinations were prospectively enrolled. Following a physical examination to confirm there were no abnormalities, a cardiac examination was performed before and during a provocative manoeuvre performed independently by two clinicians. The provocative manoeuvre was performed on the right side of the chest wall by applying gentle pressure with a stethoscope to ascertain whether a murmur became audible, graded using a modified descriptive scale (soft\/moderate). The cat's heart rate before and during the provocative manoeuvre and their age, sex, body condition score and bodyweight were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and six cats were prospectively enrolled. The average prevalence of iatrogenic murmurs was 28.2% with good interobserver agreement recorded on both the presence (kappa 0.67 and 0.62) and grade of the murmur (kappa 0.6 and 0.53). A significant association was noted between age and body condition score, with iatrogenic murmurs more likely in cats with increasing age and decreasing body condition score. There was no association between heart rate and the presence of an iatrogenic murmur.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>Iatrogenic murmurs are a common finding in cats with increasing prevalence noted in older and lean cats. Iatrogenic murmurs should therefore be considered as a differential diagnosis in a cat when an audible soft systolic right\u2010sided murmur occurs with gentle pressure application to the chest wall during auscultation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13498","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T22:55:02Z","timestamp":1647989702000},"page":"597-602","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of iatrogenic heart murmurs in a population of apparently healthy cats"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8468-884X","authenticated-orcid":false,"given":"K. L.","family":"Howell","sequence":"first","affiliation":[{"name":"Sarah Smith Cardiology, Ivy Court  Etwall Derby DE65 6JG UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6898-7900","authenticated-orcid":false,"given":"L.","family":"Ferasin","sequence":"additional","affiliation":[{"name":"Specialist Veterinary Cardiology Consultancy  Alton Hampshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Walls","sequence":"additional","affiliation":[{"name":"Broad Lane Vets  Coventry CV5 7AQ UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Smith","sequence":"additional","affiliation":[{"name":"Broad Lane Vets  Coventry CV5 7AQ UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"1991","author":"Altman D. 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