{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T22:40:53Z","timestamp":1786574453033,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T00:00:00Z","timestamp":1657324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the prognostic utility of the quick sequential organ failure assessment score in\u00a0dogs with severe sepsis and septic shock presenting to an emergency service, and evaluate the clinical value of the quick sequential organ failure assessment score to predict severe sepsis and septic shock.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The quick sequential organ failure assessment score was calculated by evaluating respiratory rate (&gt;22 breaths per minute), arterial systolic blood pressure (\u2264100\u2009mmHg) and altered mentation. The quick sequential organ failure assessment scores with respiratory rate cut\u2010offs of greater than 22, greater than 30 and greater than 40 were compared. Cases were defined as dogs presented to the emergency room and met at least 2 systemic inflammatory response syndrome criteria, had documented infection, and at least one organ dysfunction. A control population of dogs included animals with non\u2010infectious systemic inflammatory response syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010five dogs with severe sepsis and septic shock and 45 dogs with non\u2010infectious systemic inflammatory response syndrome were included in the final analysis. The quick sequential organ failure assessment provided poor discrimination between survivors and non\u2010survivors for severe sepsis and septic shock (area under receiving operating characteristic curve, 0.51; 95% confidence interval, 0.35 to 0.67). Discrimination remained poor when quick sequential organ failure assessment greater than 30 and quick sequential organ failure assessment greater than 40 scores were calculated (area under receiving operating characteristic curve, 0.56; 95% confidence interval, 0.39 to 0.72, and 0.54; 95% confidence interval, 0.36 to 0.71). The quick sequential organ failure assessment of at least 2, quick sequential organ failure assessment greater than 30 of at least 2 and quick sequential organ failure assessment greater than 40 of at least 2 produced sensitivity and specificity to detect severe sepsis and septic shock of 66.7% and 64.5%, 62.2% and 71.1%, 44.4% and 80%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and Clinical significance<\/jats:title><jats:p>Scoring systems utilised in emergency rooms should have high sensitivity to reduce missed sepsis cases and treatment delays. The use of the quick sequential organ failure assessment for severe sepsis and septic shock demonstrated poor mortality prediction and low sensitivity to detect canine patients with severe sepsis and septic shock and should not be used alone when screening for sepsis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13522","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T08:57:12Z","timestamp":1657357032000},"page":"739-746","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of quick sequential organ failure scores in dogs with severe sepsis and septic shock"],"prefix":"10.1111","volume":"63","author":[{"given":"A.\u2010M.","family":"Osgood","sequence":"first","affiliation":[{"name":"Emergency &amp; Critical Care Department Texas A&amp;M University College Station Texas USA"},{"name":"Texas A&amp;M University Veterinary Medical Teaching Hospital College Station Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Hollenbeck","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University Veterinary Medical Teaching Hospital College Station Texas USA"},{"name":"Surgery Department Texas A&amp;M University College Station Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Yankin","sequence":"additional","affiliation":[{"name":"Emergency &amp; Critical Care Department Texas A&amp;M University College Station Texas USA"},{"name":"Texas A&amp;M University Veterinary Medical Teaching Hospital College Station Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.249.1.65"},{"key":"e_1_2_6_3_1","volume-title":"Small Animal Critical Care Medicine","author":"Boller E. 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