{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T10:32:35Z","timestamp":1784716355476,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009449","name":"Petplan Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Feline herpesvirus (FHV), feline calicivirus (FCV) and <jats:italic>Chlamydia felis<\/jats:italic> are common causes of upper respiratory tract disease (URTD) in cats. Their prevalence in the UK pet cat population has not been reported and little is known regarding the risk factors for their oral carriage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Total nucleic acid was extracted from owner\u2010collected buccal swabs (n=600) from cats enrolled in a self\u2010selected longitudinal cohort study. Duplex quantitative PCRs for the detection of FHV and <jats:italic>C. felis<\/jats:italic> genomic DNA and reverse\u2010transcriptase quantitative PCRs for the detection of FCV genomic RNA were performed. Duplicates, swabs with insufficient host DNA\/RNA, and cats with missing data were excluded. Selected epidemiological data were interrogated using univariable and multi\u2010variable logistic regression modelling to identify risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data from 430 cats were included in the final statistical model. Of these, 2.1% (n=9\/430; 95% CI 1.0% to 3.9%) were positive for FHV, 13.3% (n=57\/430; 95% CI 10.2% to 16.8%) positive for FCV and 1.2% (n=5\/430; 95% CI 0.4% to 2.7%) positive for <jats:italic>C. felis<\/jats:italic>. FCV co\u2010infection was present in five (44%) FHV\u2010positive cats and three (60%) <jats:italic>C. felis<\/jats:italic>\u2010positive cats. FCV carriage was more frequent in purebred cats (odds ratio 2.48; 95% CI 1.37 to 4.49) and in cats with current or historical clinical signs compatible with URTD (odds ratio 2.98; 95% CI 1.22 to 7.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>FCV was the most frequently encountered URTD pathogen in this sample of cats; this should be noted for disinfectant choice. In cats suspected of having FHV or <jats:italic>C. felis<\/jats:italic> infection, assessment for co\u2010infection with FCV is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13623","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T05:49:33Z","timestamp":1685425773000},"page":"552-560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prevalence and risk factors for common respiratory pathogens within a cohort of pet cats in the <scp>UK<\/scp>"],"prefix":"10.1111","volume":"64","author":[{"given":"I.","family":"Chan","sequence":"first","affiliation":[{"name":"Internal Medicine Small Animal Specialist Hospital  Sydney New South Wales Australia"},{"name":"Bristol Veterinary School University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Dowsey","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Lait","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4059-1402","authenticated-orcid":false,"given":"S.","family":"Tasker","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"},{"name":"The Linnaeus Medical Team Linnaeus Group  Solihull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Blackwell","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. R.","family":"Helps","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"},{"name":"Langford Vets University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. N.","family":"Barker","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School University of Bristol  Langford UK"},{"name":"Langford Vets University of Bristol  Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-009-0337-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15588450"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-017-0467-9"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2000.0084"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.2_12431"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X16634387"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.009"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.26444\/aaem\/100655"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.128.4.77"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.156.21.669"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X16643123"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.68.6.643"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X21991456"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2004.09.017"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268812002373"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15588448"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2011.08.035"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-007-3454-1"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2003.08.008"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1971.tb06226.x"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.004"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2006.04.004"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2003.tb02517.x"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01309549"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15569615"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181f44abc"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1970.tb15929.x"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1981.tb05787.x"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(01)00340-6"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1999.tb02172.x"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.003"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2008.04.002"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1974.tb06538.x"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.101362"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1988.tb02293.x"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.103859"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T05:45:28Z","timestamp":1694411128000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.13623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,29]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/jsap.13623"],"URL":"https:\/\/doi.org\/10.1111\/jsap.13623","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,29]]},"assertion":[{"value":"2022-10-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}