{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T16:53:25Z","timestamp":1769100805501,"version":"3.49.0"},"reference-count":58,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T00:00:00Z","timestamp":1728172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>A 3\u2010year\u2010old male neutered Golden Retriever with nasal swelling and lymphadenopathy was diagnosed with diffuse <jats:italic>Mycobacterium avium<\/jats:italic> infection. Treatment with 9\u2009months of enrofloxacin, clarithromycin and rifampicin was successful, but relapsed 10\u2009months later with lymphadenopathy, skin plaques and testicular involvement. Repeat treatment for 12\u2009months was effective but 15\u2009months later a second relapse responded to the same therapy which is ongoing with survival from diagnosis of 82\u2009months. A 1\u2010year\u2010old male neutered Portuguese Podengo was diagnosed with polyarthritis and <jats:italic>M. avium<\/jats:italic> infection and treated with enrofloxacin, clarithromycin and rifampicin for 4\u2009months but relapsed, subsequently responding to combined pradofloxacin, rifampicin, doxycycline and ethambutol. After 12\u2009months of treatment, <jats:italic>M. avium<\/jats:italic> was detected and treatment extended to 17\u2009months before stopping when no organism was detected. Relapse occurred after 6\u2009weeks, responding to retreatment but relapsing (polyarthropathy, lymphadenomegaly) after 15\u2009months, with euthanasia 38\u2009months after diagnosis. Dogs with <jats:italic>M. avium<\/jats:italic> are challenging to treat with frequent relapse; however, long\u2010term survival is possible.<\/jats:p>","DOI":"10.1111\/jsap.13788","type":"journal-article","created":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T23:29:38Z","timestamp":1728257378000},"page":"838-844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Response to treatment, relapse and outcome of two dogs treated for <i>Mycobacterium avium<\/i> infection"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5322-5387","authenticated-orcid":false,"given":"V.","family":"Coates","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Lumbry Park Veterinary Specialists  Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Lumbry Park Veterinary Specialists  Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"D'Aout","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Lumbry Park Veterinary Specialists  Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Sanchez Jimenez","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging Lumbry Park Veterinary Specialists  Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"O'Halloran","sequence":"additional","affiliation":[{"name":"Division of Infection and Immunity The Royal (Dick) School of Veterinary Studies  Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,6]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"StatPearls","author":"Akram S.M.","year":"2023"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000221"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2005.06.004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638717713795"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2002.tb00281.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1981.tb01397.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcam.2022.100698"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638711418616"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(65)90010-4"},{"key":"e_1_2_7_11_1","first-page":"1563","article-title":"Tuberculosis in five basset hounds","volume":"192","author":"Carpenter J.L.","year":"1988","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_7_12_1","first-page":"59","article-title":"Mycobacterium avium complex infection in a dog","volume":"23","author":"Cucchi E.","year":"2009","journal-title":"Veterin\u00e1ria"},{"key":"e_1_2_7_13_1","first-page":"199","article-title":"Acute lameness in a cat with disseminated mycobacteriosis","volume":"56","author":"De Lorenzi G.","year":"2020","journal-title":"Veterinaria Italiana"},{"key":"e_1_2_7_14_1","first-page":"1336","article-title":"Disseminated tuberculosis caused by Mycobacterium avium in a cat","volume":"189","author":"Drolet R.","year":"1986","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063879700900416"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12088"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201301-013FR"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098587901600312"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.13420"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40588-020-00145-5"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.162.18.594"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1406.071463"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12053"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-8975"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2022.2113166"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/vetreccr-2014-000168"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2000.tb11781.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.19-0492"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1995.207.04.0457"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098589403100418"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.15-0285"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-16117-2"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0450.2004.00803.x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/597847"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.4046\/trd.2018.0060"},{"key":"e_1_2_7_36_1","first-page":"234","article-title":"Treatment of Mycobacterium avium infection in a dog","volume":"42","author":"Lam A.","year":"2012","journal-title":"Australian Veterinary Practitioner"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.ARBA-0023-2017"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.12.8629"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01104.x"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-31-3-213"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-61054-x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.16013"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.5326\/0410128"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.12968\/coan.2017.22.6.325"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.12969"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870501700220"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02283-12"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/vetreccr-2019-000934"},{"key":"e_1_2_7_49_1","first-page":"1829","article-title":"Nontuberculous Mycobacerterial infection of the head and neck in immunocompetent children: CT and MR findings","volume":"20","author":"Robson C.D.","year":"1999","journal-title":"American Journal of Neuroradiology"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.2.334-339.2006"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063878900100319"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105311"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.160.4.131"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082541"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2006.05.003"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.008854-0"},{"key":"e_1_2_7_57_1","first-page":"295","article-title":"Canine mycobacteriosis \u2013 a case\u2010report","volume":"20","author":"Walsh K.M.","year":"1984","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2022.06.025"},{"key":"e_1_2_7_59_1","first-page":"419","article-title":"A case of disseminated tuberculosis in a dog caused by Mycobacterium avium intracellulare","volume":"30","author":"Zeiss C.J.","year":"1994","journal-title":"Journal of the American Animal Hospital Association"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13788","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T01:14:57Z","timestamp":1731287697000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.13788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,6]]},"references-count":58,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/jsap.13788"],"URL":"https:\/\/doi.org\/10.1111\/jsap.13788","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,6]]},"assertion":[{"value":"2024-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}