{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T03:05:36Z","timestamp":1774321536763,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study was to confirm the accuracy of a new portable beta prototype glucometer device for monitoring blood glucose levels in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>One hundred and three client\u2010owned dogs with dysglycemia or normoglycemia were enrolled. A 3\u2009mL whole blood sample was collected from a peripheral vein from each dog and divided into four aliquots. Blood glucose was measured from three of the aliquots on the beta prototype glucometer in triplicate. The remaining aliquot was used to measure packed cell volume, total solids, and blood glucose via a reference laboratory chemistry analyzer. Accuracy was assessed in accordance with the International Organization for Standardization guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analytical performance of the beta prototype met the International Organization for Standardization accuracy requirements, with 95.1% of measurements falling within the International Organization for Standardization accuracy threshold as well as 100% of measurements being within zones A and B of the consensus error grid. Within the full range of glucose concentrations (20 to 750\u2009mg\/dL) the mean difference between the AT3 and reference lab analyzer was 2.53\u2009mg\/dL (95% limit of agreement: \u221245.27 to 50.34).<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The beta prototype glucometer device had a strong correlation with the reference laboratory standard and can be used confidently in clinical patients for the accurate monitoring of blood glucose levels in dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13847","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T22:50:00Z","timestamp":1741733400000},"page":"451-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["High concordance of blood glucose measurement in dogs between a beta prototype glucometer device and a reference laboratory standard in a clinical setting"],"prefix":"10.1111","volume":"66","author":[{"given":"K.","family":"Palladino","sequence":"first","affiliation":[{"name":"Massachusetts Veterinary Referral Hospital  Woburn Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Velineni","sequence":"additional","affiliation":[{"name":"Zoetis Veterinary Medicine Research and Development  Kalamazoo Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Zoetis Veterinary Medicine Research and Development  Kalamazoo Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Zoetis Veterinary Medicine Research and Development  Kalamazoo Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1148-2589","authenticated-orcid":false,"given":"S. D.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Ethos Veterinary Health  Woburn Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.16820"},{"key":"e_1_2_7_3_1","volume-title":"Measurement procedure comparison and bias estimation using patient samples; approved guideline","author":"Budd J.R.","year":"2013"},{"key":"e_1_2_7_4_1","first-page":"343","article-title":"Human versus veterinary POC glucometers","volume":"247","author":"Clemmons E.A.","year":"2015","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01326"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.235.3.276"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/193229681200600302"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14355"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15930"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.23.02.0024"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12310"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2271"},{"key":"e_1_2_7_13_1","first-page":"642","article-title":"Hypoglycemia in dogs: causes, management, and diagnosis","volume":"59","author":"Idowu O.","year":"2018","journal-title":"The Canadian Veterinary Journal"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.594"},{"key":"e_1_2_7_15_1","volume-title":"ISO 15197:2013: in\u00a0vitro diagnostic test systems \u2013 requirements for blood\u2010glucose monitoring systems for self\u2010testing in managing diabetes mellitus","author":"ISO","year":"2013"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.235.11.1309"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.247.9.1027"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.246.3.307"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.80.12.1074"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15657"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12911"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.8.1143"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.72.9.1204"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/10406387231195386"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/10406387211019755"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.23.08.0457"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1024\/0036-7281.151.9.448"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T11:08:00Z","timestamp":1751627280000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.13847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,25]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/jsap.13847"],"URL":"https:\/\/doi.org\/10.1111\/jsap.13847","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"value":"0022-4510","type":"print"},{"value":"1748-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,25]]},"assertion":[{"value":"2024-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}