{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:52:23Z","timestamp":1757587943867,"version":"3.43.0"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This article aims to analyse the safety of canine blood donation by describing the frequency and causes of any adverse reactions in donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In this prospective study, any blood donor adverse reactions detected by the clinical staff during and immediately after donation were recorded. The owners of the dogs were also surveyed by a veterinary practitioner or veterinary nurse 3\u2009days after donation, using a predefined questionnaire to assess for any clinical or behavioural changes. Data were collected between December 2020 and December 2021 from blood donors enrolled in an animal blood bank programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From the 4439 blood donations, 37 (0.83%) adverse post\u2010donation reactions were reported, with no other reactions identified in the remaining 4402 donations (99.17%). Of the total of donations in the studied period, 0.63% (<jats:italic>n<\/jats:italic>\u2009=\u200928) of canine donors developed a haematoma in the puncture area, 0.11% (<jats:italic>n<\/jats:italic>\u2009=\u20095) developed mild bleeding at the puncture site during the monitoring period, 0.045% (<jats:italic>n<\/jats:italic>\u2009=\u20092) developed a skin rash after clipping for donation, and 0.045% (<jats:italic>n<\/jats:italic>\u2009=\u20092) developed acute weakness, pallor, tachycardia and tachypnoea during the 30\u2009minutes monitoring period, consistent with hypotension. In both cases showing acute signs of weakness, pallor, tachycardia and tachypnoea, all parameters stabilised and resolved within 10 to 15\u2009minutes upon administration of a 10\u2009mL\/kg bolus over 10\u2009minutes of intravenous NaCl. No other delayed reactions were reported by the owners other than the acute reactions already registered by the donation staff.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The low incidence of post\u2010donation reactions in this study is encouraging, suggesting that a high level of safety can be achieved in a structured canine blood donation programme.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13861","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T01:00:21Z","timestamp":1743642021000},"page":"556-560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and characteristics of adverse reactions in dogs donating blood"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0390-7239","authenticated-orcid":false,"given":"H. C. M.","family":"Ferreira","sequence":"first","affiliation":[{"name":"Animal Blood Bank  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. R. F.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Animal Blood Bank  Porto Portugal"},{"name":"Animal Blood Bank  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. C. P.","family":"Pinto","sequence":"additional","affiliation":[{"name":"Animal Blood Bank  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Mesa\u2010Sanchez","sequence":"additional","affiliation":[{"name":"Animal Blood Bank  Barcelona Spain"},{"name":"A\u00fana Especialidades Veterinarias  Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X211020295"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939\u20101676.2005.tb02775.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327604jaws0902_3"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/0001-3765201520140210"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12900"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2020.07.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2022.09.030"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12640"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2824.2009.01269.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2003.00368.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15130"},{"volume-title":"Relat\u00f3rio de atividade transfusional e sistema portugu\u00eas de hemovigil\u00e2ncia","year":"2015","author":"Sousa G.","key":"e_1_2_8_13_1"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105281"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03202.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118933053"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11113229"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20103148.2005.00600.x"}],"container-title":["Journal of Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsap.13861","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T02:37:24Z","timestamp":1755052644000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsap.13861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,2]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1111\/jsap.13861"],"URL":"https:\/\/doi.org\/10.1111\/jsap.13861","archive":["Portico"],"relation":{},"ISSN":["0022-4510","1748-5827"],"issn-type":[{"type":"print","value":"0022-4510"},{"type":"electronic","value":"1748-5827"}],"subject":[],"published":{"date-parts":[[2025,4,2]]},"assertion":[{"value":"2023-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}