{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:10:07Z","timestamp":1779163807314,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>Acute canine polyradiculoneuritis is one of the most common lower motor neuron diseases in dogs. Given similarities to Guillain\u2013Barr\u00e9 syndrome in people, an immune\u2010mediated component has long been suspected. In veterinary medicine, two studies have documented specific antibodies as serum biomarkers for acute canine polyradiculoneuritis, including anti\u2010GM2 and anti\u2010GalNAc\u2010GD1a immunoglobulin G anti\u2010glycolipid antibodies. This case report documents the first use of membrane\u2010based therapeutic plasma exchange for the management of acute canine polyradiculoneuritis as well as an overall reduction in anti\u2010GM2 IgG and anti\u2010GalNAc\u2010GD1a IgG with subsequent treatments. The clinical recovery in this dog was rapid, with improved motor function within 48\u2009hours of her first treatment and a complete return to normal within 1\u2009month.<\/jats:p>","DOI":"10.1111\/jsap.13885","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T01:05:16Z","timestamp":1749085516000},"page":"747-750","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The use of membrane\u2010based therapeutic plasma exchange for the management of acute canine polyradiculoneuritis and reduction of antigen\u2010specific\n                    <scp>IgG<\/scp>\n                    in one dog"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8158-6393","authenticated-orcid":false,"given":"Z. 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