{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:40:11Z","timestamp":1793392811202,"version":"4.5.0"},"reference-count":50,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre\u2010 and post\u2010referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Retrospective review of medical records (signalment, clinical signs, treatments prior to referral, investigations, response to therapy and outcomes) of 75 client\u2010owned dogs diagnosed with canine chronic idiopathic rhinitis between December 2018 and 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty\u2010one males and 34 females were included. Duration of clinical signs prior to referral was 104\u2009days [3 to 1954] and only 11\/75 dogs had not received antibiotics. Tomography revealed destructive rhinitis in 54\/75 dogs. After referral, the most common first\u2010line treatment was non\u2010steroidal anti\u2010inflammatory drugs (46\/75). Sixty\u2010seven cases were followed up for 237\u2009days [14 to 1701]. Forty\u2010six, 25 and 13 dogs underwent a second, third and fourth treatment trial, respectively. Antibiotics were the most used second trial agent (25\/46), and corticosteroids the most common third (16\/25). Outcomes were available for 63 dogs. At final recorded contact, 14\/63 cases were in remission, 38\/63 were considered improved, 9\/63 had static disease and 2\/63 had worse disease. Three cases were euthanased due to canine chronic idiopathic rhinitis. Non\u2010steroidal anti\u2010inflammatory drugs were significantly associated with clinical improvement after initial treatment trial (OR: 3.0, 95% CI: 1.1 to 8.5;\n                      <jats:italic>P<\/jats:italic>\n                      =.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>Dogs diagnosed with canine chronic idiopathic rhinitis received variable therapies, including frequent antibiotics. Administration of non\u2010steroidal anti\u2010inflammatory drugs as first\u2010line treatment was associated with improved outcomes in this cohort of dogs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.70086","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T04:05:02Z","timestamp":1768622702000},"page":"460-470","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Canine chronic idiopathic rhinitis: management and outcome \u2013 a single\u2010centre retrospective observational study"],"prefix":"10.1111","volume":"67","author":[{"given":"P. M. N.","family":"Henry","sequence":"first","affiliation":[{"name":"The University of Edinburgh Hospital for Small Animals  Roslin UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Rizzo","sequence":"additional","affiliation":[{"name":"The University of Edinburgh Hospital for Small Animals  Roslin UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Tan","sequence":"additional","affiliation":[{"name":"The University of Edinburgh Hospital for Small Animals  Roslin UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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