{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T02:02:50Z","timestamp":1789351370802,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"abstract":"\n Objective<\/jats:title>\n \n Diet is an integral component of the management of chronic enteropathy in dogs. The role of insect\u2010based diets in this disease remains unknown. The objective of this study was to evaluate the impact of an insect\u2010based (\n Hermetia illucens<\/jats:italic>\n ) diet in dogs with presumed food\u2010responsive enteropathy.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Twenty\u2010seven client\u2010owned dogs with evidence of chronic enteropathy, in which diet was required as sole management, were enrolled onto this prospective, uncontrolled diet trial. Canine inflammatory bowel disease activity index, faecal score, body condition score and body weight (kg) were recorded pre\u2010enrolment (T\n 0<\/jats:sub>\n ). Dogs were exclusively fed insect diet and reassessed at 14 (T\n 1<\/jats:sub>\n ), 30 (T\n 2<\/jats:sub>\n ) and 90 (T\n 3<\/jats:sub>\n ) days. Dogs remained in the study if responding and exited the study at various times for additional investigations or alternative treatment(s) if not responding. Comparisons were made within responders over time and between responders and non\u2010responders at T\n 0<\/jats:sub>\n . Data are expressed as median (range).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Twenty\u2010seven dogs were recruited; seven cases were withdrawn, leaving 20 dogs for analysis. Fourteen\/20 dogs (70%) were classified as responders with a decrease in median faecal score from 6.25 (5 to 7) at T\n 0<\/jats:sub>\n to 2 (2 to 5) at T\n 1<\/jats:sub>\n and a median decrease in canine inflammatory bowel disease activity index from 8 (5 to 14) at T\n 0<\/jats:sub>\n to 1 (0 to 5) at T\n 1<\/jats:sub>\n . All responders had adequate control at day 90 (T\n 3<\/jats:sub>\n ), with a median faecal score of 2 (2 to 5) and a median canine inflammatory bowel disease activity index of 0 (0 to 3).\n <\/jats:p>\n <\/jats:sec>\n \n Clinical Significance<\/jats:title>\n Insect diet improved clinical signs in 70% of chronic enteropathy dogs and could represent another dietary option in the management of this disease.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jsap.70195","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T01:06:46Z","timestamp":1789348006000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful use of insect\u2010based (\n Hermetia illucens<\/i>\n ) diet in dogs with food\u2010responsive enteropathy"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3898-5085","authenticated-orcid":false,"given":"K.","family":"Murtagh","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine University College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6710-2074","authenticated-orcid":false,"given":"E.","family":"Stavroulaki","sequence":"additional","affiliation":[{"name":"Dick White Referrals Veterinary Specialists Cambridgeshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5393-223X","authenticated-orcid":false,"given":"M.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinary Research (CiiEM) Egas Moniz School of Health & Science Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5882-7797","authenticated-orcid":false,"given":"E.","family":"J. O'Neill","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8690-0776","authenticated-orcid":false,"given":"C. T.","family":"Mooney","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","DOI":"10.3390\/ani11092525","article-title":"Insect larvae meal (Hermetia illucens) as a sustainable protein source of canine food and its impacts on nutrient digestibility and fecal quality","volume":"11","author":"Abd El\u2010Wahab A.","year":"2021","journal-title":"Animals"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/vr.103557","article-title":"Long\u2010term outcome in dogs with chronic enteropathies: 203 cases","volume":"178","author":"Allenspach K.","year":"2016","journal-title":"The Veterinary 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Heimtiere"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","DOI":"10.3390\/ani14192859","article-title":"An assessment of the impact of insect meal in dry food on a dog with a food allergy: a case report","volume":"14","author":"Cesar C.G.L.","year":"2024","journal-title":"Animals"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/jsap.12588","article-title":"Inflammatory bowel disease versus chronic enteropathy in dogs: are they one and the same?","volume":"57","author":"Dandrieux J.R.","year":"2016","journal-title":"Journal of Small Animal Practice"},{"key":"e_1_2_6_9_1","first-page":"203","article-title":"Chronic enteropathy in canines: prevalence, impact and management strategies","volume":"10","author":"Dandrieux J.R.S.","year":"2019","journal-title":"Veterinary Medicine (Auckland, N.Z.)"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202000324","article-title":"In vitro studies toward the use of chitin as nutraceutical: impact on the intestinal epithelium, macrophages, and microbiota","volume":"64","author":"Dong L.","year":"2020","journal-title":"Molecular Nutrition & Food Research"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","DOI":"10.3390\/ani14050681","article-title":"Updating the classification of chronic inflammatory enteropathies in dogs","volume":"14","author":"Dupouy\u2010Manescau N.","year":"2024","journal-title":"Animals"},{"key":"e_1_2_6_12_1","first-page":"1","article-title":"Increased dietary fiber intake improves fecal and clinical activity scores in dogs with chronic enteropathy","volume":"264","author":"Ford\u2010Hrymak D.B.","year":"2026","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12917-025-04528-y","article-title":"An extensively hydrolysed protein\u2010based extruded diet in the treatment of dogs with chronic enteropathy and at least one previous diet\u2010trial failure: a pilot uncontrolled open\u2010label study","volume":"21","author":"Freiche V.","year":"2025","journal-title":"BMC Veterinary Research"},{"key":"e_1_2_6_14_1","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1111\/jvim.17161","article-title":"Long\u2010term evaluation of the initial response to therapy in 60 dogs with chronic inflammatory enteropathy","volume":"38","author":"Hodel S.","year":"2024","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","DOI":"10.1111\/jvim.70147","article-title":"Treatment of Hypovitaminosis D with cholecalciferol in dogs with protein\u2010losing enteropathies: a randomized, double\u2010blind, placebo\u2010controlled, clinical trial","volume":"39","author":"Jablonski S.A.","year":"2025","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1111\/jvim.16846","article-title":"Efficacy of an elemental diet in achieving clinical remission in dogs with chronic enteropathy","volume":"37","author":"Manchester A.C.","year":"2023","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1111\/j.1939-1676.2010.0632.x","article-title":"A randomized, open\u2010label, positively\u2010controlled field trial of a hydrolyzed protein diet in dogs with chronic small bowel enteropathy","volume":"24","author":"Mandigers P.J.","year":"2010","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.653411","article-title":"In vivo and in\u00a0vitro digestibility of an extruded complete dog food containing black soldier fly (Hermetia illucens) larvae meal as protein 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