{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:37:04Z","timestamp":1792816624756,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Macrodontia is a common dental pathology in guinea pigs and a frequent cause of malocclusion. While its clinical and radiographic features have been described, the tomographic appearance of macrodontic teeth using cone\u2010beam computed tomography (CBCT) has not been previously reported. To characterise the CBCT features of macrodontic teeth in guinea pigs and to assess associated structural and alveolar changes based on retrospective analysis of clinically indicated imaging data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>CBCT datasets from 62 guinea pigs were reviewed retrospectively. Forty\u2010two cases with at least one macrodontic tooth were included. A total of 666 cheek teeth were evaluated, including 104 teeth with structural changes characteristic of macrodontia. Premolar and molar alveoli were assessed using a four\u2010grade scoring system, and tooth circumference measurements were obtained. Structural alterations were classified as isodense or heterodense.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Macrodontic teeth had significantly greater circumferences than non\u2010macrodontic teeth (mean 17.70\u2009mm\n                      <jats:italic>vs.<\/jats:italic>\n                      15.13\u2009mm;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Advanced alveolar remodelling (grades 2\u20133) was associated with 84.6% of macrodontic teeth, compared with 23.8% of non\u2010macrodontic teeth. Loss of dental substance at occlusal margins occurred predominantly in macrodontic teeth and was associated with widening of periodontal and interdental spaces.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>CBCT enables detailed three\u2010dimensional assessment of macrodontic tooth structure, size, and periapical changes in guinea pigs, providing clinically relevant information not achievable with conventional radiography.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jsap.70217","type":"journal-article","created":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:46:45Z","timestamp":1792813605000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cone\u2010beam computed tomographic features of macrodontic cheek teeth (premolars and molars) in guinea pigs"],"prefix":"10.1111","author":[{"given":"J.","family":"Ignaszak\u2010Dziech","sequence":"first","affiliation":[{"name":"Center for the Diagnosis and Treatment of Exotic Animals Veterinary Clinic \u201cZwierzyniec\u201d  Wroc\u0142aw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2934-1688","authenticated-orcid":false,"given":"T.","family":"Piasecki","sequence":"additional","affiliation":[{"name":"Department of Epizootiology and Clinic of Bird and Exotic Animals, Faculty of Veterinary Medicine University of Environmental and Life Sciences  Wroc\u0142aw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/vru.12101","article-title":"Computed tomographic characteristics of odontogenic neoplasms in dogs","volume":"55","author":"Amory 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