{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T01:06:53Z","timestamp":1775005613933,"version":"3.50.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Sacral neuromodulation is a well-established treatment for urinary and bowel disorders with potential use for other disorders such as sexual dysfunction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To evaluate changes in sexual functioning in women undergoing neuromodulation for voiding symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients enrolled in our prospective, observational neuromodulation database study were evaluated. Data were collected from medical records, and patient-completed Female Sexual Function Index (FSFI) and Interstitial Cystitis Symptom-Problem Indices (ICSI-PI) at baseline, 3, 6, and 12 months post-implant. Patients rated overall change in sexual functioning on scaled global response assessments (GRA) at 3, 6, and 12 months post-implant. We grouped women by baseline FSFI scores: less (score &amp;lt; 26) and more sexually functional (score \u2265 26). Data were analyzed with Pearson's Chi-square or Fisher's Exact test and repeated measures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcomes Measures<\/jats:title>\n                  <jats:p>Changes in FSFI and ICSI-PI scores in women grouped by baseline FSFI score &amp;lt; 26 and \u226526.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 167 women evaluated, FSFI scores improved overall from preimplant (mean 13.5 \u00b1 8.5) to 12 months (N = 72; mean 15.9 \u00b1 8.9, P = 0.004). At baseline and each follow-up point, ICSI-PI scores were similar between groups and improved through time. For patients in the FSFI &amp;lt; 26 group there was improvement from baseline to 12-month scores (N = 63; 11.9 \u00b1 6.9 to 14.8 \u00b1 8.7; P = 0.0006). Improved FSFI domains included desire, orgasm, satisfaction, and pain. Furthermore, of the 74 subjects in this group not sexually active at baseline, 10 became sexually active during follow-up. In the FSFI \u2265 26 group there was slight but statistically significant decline in mean scores between baseline and 12 months (N = 9; 27.4 \u00b1 1.1 to 24.5 \u00b1 3.4; P = 0.0302); however one had become sexually inactive. A significant decrease was seen in the satisfaction domain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Many factors affect sexual functioning in women; however sexual function may improve along with urinary symptoms after neuromodulation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12085","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T20:58:39Z","timestamp":1361998719000},"page":"2477-2483","source":"Crossref","is-referenced-by-count":28,"title":["Changes in Sexual Functioning in Women After Neuromodulation for Voiding Dysfunction"],"prefix":"10.1093","volume":"10","author":[{"given":"Jessica M.","family":"Yih","sequence":"first","affiliation":[{"name":"Department of Urology, Beaumont Health System , Royal Oak, MI , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim A.","family":"Killinger","sequence":"additional","affiliation":[{"name":"Department of Urology, Beaumont Health System , Royal Oak, MI , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith A.","family":"Boura","sequence":"additional","affiliation":[{"name":"Department of Urology, Beaumont Health System , Royal Oak, MI , USA"},{"name":"Oakland University William Beaumont School of Medicine , Rochester, MI , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth M.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Urology, Beaumont Health System , Royal Oak, MI , USA"},{"name":"Oakland University William Beaumont School of Medicine , Rochester, MI , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,10,1]]},"reference":[{"key":"2024032602341224400_bib1","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1111\/j.1743-6109.2010.01778.x","article-title":"Definitions\/epidemiology\/risk factors for sexual factors for sexual dysfunction","volume":"7","author":"Lewis","year":"2010","journal-title":"J Sex Med"},{"key":"2024032602341224400_bib2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/sj.ijir.3901440","article-title":"Female sexual dysfunction in a population-based study in Iran: Prevalence and associated risk factors","volume":"18","author":"Safarinejad","year":"2006","journal-title":"Int J Impot Res"},{"key":"2024032602341224400_bib3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s00192-011-1583-0","article-title":"Incontinence during intercourse: Myths unravelled","volume":"23","author":"Jha","year":"2012","journal-title":"Int Urogynecol J"},{"key":"2024032602341224400_bib4","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/sj.ijir.3901296","article-title":"Sexual function in women with urinary incontinence","volume":"17","author":"Aslan","year":"2005","journal-title":"Int J Impot Res"},{"key":"2024032602341224400_bib5","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.eururo.2003.11.023","article-title":"Sexual dysfunction is common in women with lower urinary tract symptoms and urinary incontinence: Results of a cross-sectional study","volume":"45","author":"Salonia","year":"2004","journal-title":"Eur Urol"},{"key":"2024032602341224400_bib6","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1002\/nau.20786","article-title":"Efficacy and adverse events of sacral nerve stimulation for overactive bladder: A systematic review","volume":"29","author":"Siddiqui","year":"2010","journal-title":"Neurourol Urodyn"},{"key":"2024032602341224400_bib7","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/DCR.0b013e31822155e9","article-title":"Long-term efficacy and safety of sacral nerve stimulation for fecal incontinence","volume":"54","author":"Mellgren","year":"2011","journal-title":"Dis Colon Rectum"},{"key":"2024032602341224400_bib8","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s00192-010-1281-3","article-title":"Sacral neuromodulation stimulation for IC\/PBS, chronic pelvic pain, and sexual dysfunction","volume":"21","author":"Fariello","year":"2010","journal-title":"Int Urogynecol J"},{"key":"2024032602341224400_bib9","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/j.1525-1403.2011.00380.x","article-title":"Improved sexual and urinary function in women with sacral nerve stimulation","volume":"14","author":"Gill","year":"2011","journal-title":"Neuromodulation"},{"key":"2024032602341224400_bib10","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1111\/j.1743-6109.2010.02189.x","article-title":"Impact of sacral neuromodulation on female sexual function and his correlation with clinical outcome and quality of life indexes: A monocentric experience","volume":"8","author":"Signorello","year":"2011","journal-title":"J Sex Med"},{"key":"2024032602341224400_bib11","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1111\/j.1743-6109.2007.00604.x","article-title":"Validation of the female sexual function index in women with chronic pelvic pain","volume":"4","author":"Verit","year":"2007","journal-title":"J Sex Med"},{"key":"2024032602341224400_bib12","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/713847100","article-title":"Validation of the Female Sexual Function Index (FSFI) in women with female orgasmic disorder and in women with hypoactive sexual desire disorder","volume":"29","author":"Meston","year":"2003","journal-title":"J Sex Marital Ther"},{"key":"2024032602341224400_bib13","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/009262300278597","article-title":"The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function","volume":"26","author":"Rosen","year":"2000","journal-title":"J Sex Marital Ther"},{"issue":"5A Suppl","key":"2024032602341224400_bib14","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0090-4295(99)80333-1","article-title":"The interstitial cystitis symptom index and problem index","volume":"49","author":"O'Leary","year":"1997","journal-title":"Urology"},{"key":"2024032602341224400_bib15","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/j.juro.2009.12.106","article-title":"Effect of amitriptyline on symptoms in treatment naive patients with interstitial cystitis\/painful bladder syndrome","volume":"183","author":"Foster","year":"2010","journal-title":"J Urol"},{"key":"2024032602341224400_bib16","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1002\/nau.20592","article-title":"The relationship between subjective and objective assessments of sacral neuromodulation effectiveness in patients with urgency-frequency","volume":"27","author":"Peters","year":"2008","journal-title":"Neurourol Urodyn"},{"key":"2024032602341224400_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00926230590475206","article-title":"The female sexual function index (FSFI): Cross-validation and development of clinical cutoff scores","volume":"31","author":"Wiegel","year":"2005","journal-title":"J Sex Marital Ther"},{"key":"2024032602341224400_bib18","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1111\/j.1743-6109.2009.01238.x","article-title":"Biofeedback, electrical stimulation, pelvic floor muscle exercises, and vaginal cones: A combined rehabilitative approach for sexual dysfunction associated with urinary incontinence","volume":"6","author":"Rivalta","year":"2009","journal-title":"J Sex Med"},{"key":"2024032602341224400_bib19","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00192-006-0168-9","article-title":"Effects of sacral neuromodulation on female sexual function","volume":"18","author":"Pauls","year":"2007","journal-title":"Int Urogynecol J"}],"container-title":["The Journal of Sexual Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743609515301363?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743609515301363?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/10\/10\/2477\/48192910\/jsm_10_10_2477.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/10\/10\/2477\/48192910\/jsm_10_10_2477.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T02:39:42Z","timestamp":1711420782000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jsm\/article\/10\/10\/2477\/6940167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,1]]},"references-count":19,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,10,1]]},"published-print":{"date-parts":[[2013,10,1]]}},"URL":"https:\/\/doi.org\/10.1111\/jsm.12085","relation":{},"ISSN":["1743-6109","1743-6095"],"issn-type":[{"value":"1743-6109","type":"electronic"},{"value":"1743-6095","type":"print"}],"subject":[],"published-other":{"date-parts":[[2013,10]]},"published":{"date-parts":[[2013,10,1]]}}}