{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T09:36:01Z","timestamp":1784453761906,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Herrmann Klaus-Stiftung Zurich"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Sexual intercourse, orgasm, and sexual satisfaction are associated with well-being and improved quality of life. The pituitary hormone prolactin (PRL) may have an important role in regulating (and thus indexing) sexual satiety and satisfaction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>Physiological indices to quantify the quality and resulting satisfaction from female orgasm would be valuable. Therefore we aim to validate associations of orgasm-induced PRL surges with women's orgasm quality and subsequent sexual satisfaction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a prospective study, with a pre-post, single-blinded, cross-over design in a naturalistic field setting, we analyzed the correlation of women's post-orgasmic serum PRL surges following sexual intercourse with women's perceived quality of orgasm and resulting sexual satisfaction, as measured by a questionnaire.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measures<\/jats:title>\n                  <jats:p>PRL levels prior to and following penile-vaginal intercourse with and without orgasm, and scores from the Acute Sexual Experience Scale (ASES) on quality of orgasm and sexual satisfaction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>An analysis of variance of the blood samples in nine women indicated large magnitude, significant effects of intercourse orgasm on PRL levels (P\u2009=\u20090.004, eta squared\u2009=\u20090.78), as well as an interaction with the effect of multiple orgasms (P\u2009=\u20090.008, eta squared\u2009=\u20090.80). PRL post\/pre ratios and arithmetic difference correlated strongly with orgasm quality (r\u2009=\u20090.85, P\u2009=\u20090.016, and r\u2009=\u20090.69, P\u2009=\u20090.08) and sexual satisfaction (r\u2009=\u20090.75, P\u2009=\u20090.05 and r\u2009=\u20090.77, P\u2009=\u20090.045).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Women's intercourse orgasm induced PRL surges are strongly related to the quality of orgasm and subsequent sexual satisfaction. This implies that post-orgasmic PRL surges are an objective index of orgasm and orgasm quality. PRL might be used in future studies on basic research as well as a treatment target in sexual disorders in women.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12097","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T21:15:41Z","timestamp":1361308541000},"page":"1313-1319","source":"Crossref","is-referenced-by-count":32,"title":["The Quality of Sexual Experience in Women Correlates with Post-Orgasmic Prolactin Surges: Results from an Experimental Prototype Study"],"prefix":"10.1093","volume":"10","author":[{"given":"Brigitte","family":"Leeners","sequence":"first","affiliation":[{"name":"Division of Reproductive Endocrinology \u00a0 , Zurich , Switzerland"},{"name":"University Hospital Zurich \u00a0 , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tillmann H.C.","family":"Kruger","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy \u00a0 , 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