{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T14:53:39Z","timestamp":1791644019064,"version":"4.3.4"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,8,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Although infertility is known to be associated with psychological and sexual problems, the relationship between these two aspects in infertile men has not been well investigated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To investigate the incidence of sexual dysfunction and psychological burden, and their possible associations in infertile men.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>From June 2009 to June 2012, a total of 1,468 infertile men and 942 fertile men were evaluated. Premature ejaculation (PE) and erectile dysfunction (ED) were measured by the PE diagnostic tool (PEDT), the intravaginal ejaculatory latency time (IELT) and the international index of erectile function (IIEF)-5. Anxiety and depression, which reflect the degree of psychological burden, were measured by the self-rating anxiety scale (SAS) and self-rating depression scale (SDS), respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measures<\/jats:title>\n                  <jats:p>PE and ED were measured by the PEDT, IELT, and IIEF-5. Anxiety and depression were measured by the SAS and SDS, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The incidences of PE and ED in the infertile group were significantly higher than those in the fertile group (PE: 19.01% vs.10.93%, P\u2009&amp;lt;\u20090.001; ED: 18.05% vs. 8.28%, P\u2009&amp;lt;\u20090.001). In addition, anxiety and depression were more prevalent in infertile than fertile men (Anxiety: 38.01% vs. 26.65%, P\u2009&amp;lt;\u20090.001; Depression: 15.74% vs. 10.08%, P\u2009&amp;lt;\u20090.001). Furthermore, after adjusting for age in the infertile group, the PEDT score was positively associated with anxiety (adjusted r\u2009=\u20090.57; P\u2009&amp;lt;\u20090.001) and depression (adjusted r\u2009=\u20090.54; P\u2009&amp;lt;\u20090.001). Moreover, the IELT were negatively associated with anxiety (adjusted r\u2009=\u2009\u22120.40; P\u2009&amp;lt;\u20090.001) and depression (adjusted r\u2009=\u2009\u22120.52; P\u2009&amp;lt;\u20090.001). Similar negative relationships were also observed between the IIEF-5 score and anxiety (adjusted r\u2009=\u2009\u22120.49; P\u2009&amp;lt;\u20090.001) or depression (adjusted r\u2009=\u2009\u22120.50; P\u2009&amp;lt;\u20090.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This is the first study to systematically evaluate the incidence of sexual dysfunction and psychological burden, and their possible associations in infertile men in China. Further in-depth studies are needed to confirm and extend these results.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12207","type":"journal-article","created":{"date-parts":[[2013,5,20]],"date-time":"2013-05-20T18:11:41Z","timestamp":1369073501000},"page":"1935-1942","source":"Crossref","is-referenced-by-count":83,"title":["Relationship Between Sexual Dysfunction and Psychological Burden in Men with Infertility: A Large Observational Study in China"],"prefix":"10.1093","volume":"10","author":[{"given":"Jingjing","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiansheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puyu","family":"Su","sequence":"additional","affiliation":[{"name":"Academy of Public Health of Anhui Medical University , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jishuang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongyao","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaozhao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Hefei, Anhui , China"},{"name":"the First Affiliated Hospital of Anhui Medical University \u00a0 , Hefei, Anhui , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,8,1]]},"reference":[{"key":"2024032602343604400_bb0010","first-page":"91","article-title":"WHO manual for the standardized investigation, diagnosis, and management of the infertile male","author":"Rowe","year":"2000"},{"key":"2024032602343604400_bb0015","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/humrep\/dem046","article-title":"International estimates of infertility prevalence and treatment-seeking: Potential need and demand for infertility medical care","volume":"22","author":"Boivin","year":"2007","journal-title":"Hum Reprod"},{"key":"2024032602343604400_bb0020","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1111\/j.1743-6109.2010.01717.x","article-title":"Sexual disorders in infertile couples","volume":"7","author":"Wischmann","year":"2010","journal-title":"J Sex Med"},{"key":"2024032602343604400_bb0025","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1111\/j.1743-6109.2009.01383.x","article-title":"Sexual, marital, and social impact of a man's perceived infertility diagnosis","volume":"6","author":"Smith","year":"2009","journal-title":"J Sex Med"},{"key":"2024032602343604400_bb0030","first-page":"1","article-title":"Infertility and psychosexual disorders: Relationship in infertile couples","volume":"54","author":"Jain","year":"2000","journal-title":"Indian J Med Sci"},{"key":"2024032602343604400_bb0035","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1111\/j.1743-6109.2012.02872.x","article-title":"Clinical correlates of erectile dysfunction and premature ejaculation in men with couple infertility","volume":"9","author":"Lotti","year":"2012","journal-title":"J Sex Med"},{"key":"2024032602343604400_bb0040","first-page":"58","article-title":"Sexual dysfunction associated with infertility. 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