{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T15:49:22Z","timestamp":1781020162861,"version":"3.54.1"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Chronic bacterial prostatitis (CBP) is reported to be a common finding in men with acquired premature ejaculation (PE). The impact of different pathogens on PE development in chronic prostatitis patients is, however, unknown.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To assess a possible link between CBP caused by Chlamydia trachomatis (Ct) and PE.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A consecutive series of 317 patients with clinical and instrumental diagnosis of CBP due to Ct was enrolled (group A) and compared with data obtained from a control group of 639 patients with CBP caused by common uropathogen bacteria (group B). Prostatitis symptoms were investigated with the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), while the ejaculatory status of patients was assessed using the PE Diagnostic Tool (PEDT).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measures<\/jats:title>\n                  <jats:p>All participants were asked to complete the NIH-CPSI, the International Index of Erectile Function-15 erectile function domain (IIEF-15-EFD), the PEDT, and the Short Form (SF)-36 questionnaires.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Patient groups A and B had comparable scores of NIH-CPSI (P = 0.07), IPSS (P = 0.32), and IIEF-15-EFD (P = 0.33) tests. PE was assessed in 118 patients in group A (37.2%) and in 73 subjects in group B (11.5%). The two groups are different in terms of PE prevalence (P &amp;lt; 0.0002). Compared with group B, group A showed significantly higher scores of the PEDT test (11.3 [\u00b12.6] vs. 4.5 [\u00b12.9], P &amp;lt; 0.0001) and lower scores of the SF-36 tool (96.5 [\u00b11.1] vs. 99.7 [\u00b11.3], P &amp;lt; 0.0001). In our multivariate model assessment, being positive for a Ct infection marker was independently associated with the PEDT score even after adjusting for age, smoking habit, body mass index, and education level (adjusted odds ratio = 3.21; 95% confidence interval: 2.02\u20134.27; P &amp;lt; 0.003).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Patients affected by CBP due to Ct infection reported higher prevalence of PE and lower quality of life when compared with patients affected by CBP caused by traditional uropathogenic bacteria.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12699","type":"journal-article","created":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T07:50:58Z","timestamp":1411631458000},"page":"3085-3092","source":"Crossref","is-referenced-by-count":14,"title":["<i>C<\/i>\n                  <i>hlamydia<\/i>\u2005<i>t<\/i>\n                  <i>rachomatis<\/i> Infection Is Related to Premature Ejaculation in Chronic Prostatitis Patients: Results from a Cross-Sectional Study"],"prefix":"10.1093","volume":"11","author":[{"given":"Tommaso","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Urology \u00a0 , Trento , Italy"},{"name":"Santa Chiara Regional Hospital \u00a0 , Trento , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pisano","sequence":"additional","affiliation":[{"name":"Department of Urology \u00a0 , Turin , Italy"},{"name":"University of Turin \u00a0 , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Magri","sequence":"additional","affiliation":[{"name":"Urology and Sonography Secondary Care Clinic \u00a0 , Milano , Italy"},{"name":"Azienda Ospedaliera Istituti Clinici di Perfezionamento \u00a0 , Milano , 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