{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:43:21Z","timestamp":1783723401429,"version":"3.55.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Although growing evidence suggests the beneficial effects of a nerve-sparing (NS) approach to surgery in cervical cancer patients, only limited data on NS laparoscopic radical hysterectomy (LRH) are available, and no studies have investigated the effects of NS-LRH on sexual function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>This study aims to determine whether the implementation of NS-LRH impacts on sexual function in cervical cancer patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Sexually active cervical cancer patients undergoing type C (class III) LRH between 2004 and 2013 were enrolled in this prospective study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measures<\/jats:title>\n                  <jats:p>Preoperative and postoperative sexual function were assessed using a validated questionnaire, the Female Sexual Function Index (FSFI). The FSFI evaluates desire, arousal, lubrication, orgasm, satisfaction, and pain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Forty patients undergoing radical hysterectomy (20 conventional LRH vs. 20 NS-LRH) represented the study group. Baseline characteristics were similar between groups (P &amp;gt; 0.05). No differences in preoperative FSFI scores were recorded (P &amp;gt; 0.05). We observed that both LRH and NS-LRH worsened postoperative FSFI scores (P &amp;lt; 0.001). However, patients undergoing NS-LRH had higher postoperative FSFI scores than patients undergoing LRH (21.3 \u00b1 9.4 vs. 14.2 \u00b1 12.5; P = 0.04). Considering postoperative domain scores, we observed that desire, arousal, orgasm, and pain scores were similar between groups (P &amp;gt; 0.05), while patients undergoing NS-LRH experienced higher lubrication (3.4 \u00b1 2.3 vs. 1.7 \u00b1 2.2; P = 0.02) and satisfaction (4.6 \u00b1 3.9 vs. 2.8 \u00b1 2.2; P = 0.004) scores in comparison with patients undergoing conventional LRH. No between-group differences in survival outcomes were found.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Both conventional LRH and NS-LRH impact negatively on patients' sexual function. However, the NS approach impairs sexual function less, minimizing the effects of radical surgery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12702","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T02:31:53Z","timestamp":1411353113000},"page":"3012-3020","source":"Crossref","is-referenced-by-count":35,"title":["Nerve-Sparing Approach Reduces Sexual Dysfunction in Patients Undergoing Laparoscopic Radical Hysterectomy"],"prefix":"10.1093","volume":"11","author":[{"given":"Giorgio","family":"Bogani","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology \u00a0 , Varese , Italy"},{"name":"University of Insubria \u00a0 , Varese , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Serati","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology \u00a0 , Varese , Italy"},{"name":"University of Insubria \u00a0 , Varese , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Nappi","sequence":"additional","affiliation":[{"name":"Research Center for Reproductive Medicine, Gynecological Endocrinology and Menopause \u00a0 , Pavia , Italy"},{"name":"IRCCS S. 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