{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:32:26Z","timestamp":1783542746121,"version":"3.55.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Stuttering priapism (SP) is seen in sickle cell disease (SCD) and characterized by short-lived painful erections. Imbalanced vascular tone is the postulated cause and this may be reflected in changes in baseline penile blood flow as measured using penile Doppler ultrasound (PDU).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>The aim of this study was to investigate the baseline penile blood flow characteristics in men with SCD and SP, by comparing with men without SP.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>PDU findings were retrospectively analyzed in 100 men during flaccid state. Nine men had SP (age range 20\u201340 years), 4 had Peyronie's disease (PD) (35\u201348 years), 67 men had erectile dysfunction (16\u201367 years), and 20 men had normal erectile function (18\u201342 years).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measures<\/jats:title>\n                  <jats:p>The variables measured were peak systolic and end-diastolic velocities, and the Doppler velocity waveform. Values in men with SP were compared with those in the other groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Median systolic and diastolic velocity was significantly higher in men with SP (systolic\/diastolic velocity was 26\/4\u2009cm\/second in men with SP vs. 13\/0\u2009cm\/second, 14\/0\u2009cm\/second, and 16\/0\u2009cm\/second in men with PD, ED, and normal erectile function, respectively; P\u2009=\u20090.0001). Men with SP had a characteristic low peripheral resistance (PR) waveform with fluctuating velocities; the diastolic velocity was consistently positive (2\u20137\u2009cm\/second) and fluctuated between +2 and +8\u2009cm\/second. In comparison, the other 91 men had high PR waveform and consistently negative diastolic velocity (range 0 to \u22122\u2009cm\/second).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Men with SP had a unique baseline Doppler ultrasound waveform, with a low PR waveform and an elevated, variable cavernosal artery velocity. We propose that this may be the sonographic manifestation of a reduced, fluctuating smooth muscle tone and that PDU may have a role for diagnosis and therapeutic monitoring of SP.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jsm.12756","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T08:37:36Z","timestamp":1416991056000},"page":"549-556","source":"Crossref","is-referenced-by-count":8,"title":["Penile Doppler Ultrasound in Men with Stuttering Priapism and Sickle Cell Disease\u2014A Labile Baseline Diastolic Velocity Is a Characteristic Finding"],"prefix":"10.1093","volume":"12","author":[{"given":"Uday","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Radiology , London , UK"},{"name":"St George's Hospital and Medical School , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunan","family":"Sujenthiran","sequence":"additional","affiliation":[{"name":"Department of Urology , London , UK"},{"name":"St George's Hospital and Medical School , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Watkin","sequence":"additional","affiliation":[{"name":"Department of Urology , London , UK"},{"name":"St George's Hospital and Medical School , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,2,1]]},"reference":[{"key":"2023012309021666500_bb0010","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1097\/01.ju.0000087608.07371.ca","article-title":"American urological association guidelines on the management of Priapism","volume":"170","author":"Montague","year":"2003","journal-title":"J Urol"},{"key":"2023012309021666500_bb0015","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1097\/00043426-199911000-00013","article-title":"Prevalence of priapism in children and adolescents with sickle cell anaemia","volume":"21","author":"Mantadakis","year":"1999","journal-title":"J Pedeatric Hematol Oncol"},{"key":"2023012309021666500_bb0020","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s11934-012-0258-9","article-title":"Stuttering priapism: Insights into pathogenesis and management","volume":"13","author":"Morrison","year":"2012","journal-title":"Curr Urol Rep"},{"key":"2023012309021666500_bb0025","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/S0140-6736(85)91555-7","article-title":"Stilboestrol and stuttering priapism in homozygous sickle-cell disease","volume":"2","author":"Sergeant","year":"1985","journal-title":"Lancet"},{"key":"2023012309021666500_bb0030","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1046\/j.1464-410X.2002.03022.x","article-title":"Priapism in sickle cell disease: Incidence, risk factors and complications\u2014An international multicentre study","volume":"90","author":"Adeyoju","year":"2002","journal-title":"BJU Int"},{"key":"2023012309021666500_bb0035","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1182\/blood.V77.7.1405.1405","article-title":"Vascular occlusion in sickle cell disease. 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