{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:39:22Z","timestamp":1791383962034,"version":"4.3.3"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T00:00:00Z","timestamp":1365379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Czech Ministry of Health","award":["IGA NT 13238-4\/2012"],"award-info":[{"award-number":["IGA NT 13238-4\/2012"]}]},{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"crossref","award":["PRVOUK-P26\/LF1\/4"],"award-info":[{"award-number":["PRVOUK-P26\/LF1\/4"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In a retrospective cohort study undertaken in 12 European countries, 249 female narcoleptic patients with cataplexy (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>216) and without cataplexy (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>33) completed a self\u2010administrated questionnaire regarding pregnancy and childbirth. The cohort was divided further into patients whose symptoms of narcolepsy started before or during pregnancy (308 pregnancies) and those in whom the first symptoms of narcolepsy appeared after delivery (106 pregnancies). Patients with narcolepsy during pregnancy were older during their first pregnancy (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001) and had a higher body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) prior to pregnancy (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.01). Weight gain during pregnancy was higher in narcoleptic patients with cataplexy (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.01). More patients with narcolepsy\u2013cataplexy during pregnancy had impaired glucose metabolism and anaemia. Three patients experienced cataplexy during delivery. The rate of caesarean sections was higher in the narcolepsy\u2013cataplexy group compared to the narcolepsy group (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05). The mean birth weight and gestational age of neonates were within the normal range and did not differ across groups. Neonatal care was affected adversely by symptoms of narcolepsy in 60.1% of those with narcolepsy during pregnancy. This study reports more obstetric complications in patients with narcolepsy\u2013cataplexy during pregnancy; however, these were not severe. This group also had a higher <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and higher incidence of impaired glucose metabolism during pregnancy. Caesarian section was conducted more frequently in narcolepsy\u2013cataplexy patients, despite cataplexy being a rare event during delivery. Furthermore, symptoms of narcolepsy may render care of the infant more difficult.<\/jats:p>","DOI":"10.1111\/jsr.12047","type":"journal-article","created":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T09:09:34Z","timestamp":1365412174000},"page":"496-512","source":"Crossref","is-referenced-by-count":56,"title":["Narcolepsy and pregnancy: a retrospective <scp>E<\/scp>uropean evaluation of 249 pregnancies"],"prefix":"10.1111","volume":"22","author":[{"given":"Eszter","family":"Maurovich\u2010Horvat","sequence":"first","affiliation":[{"name":"Department of Neurology and Center of clinical Neuroscience First Faculty of Medicine Charles University and General University Hospital Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kemlink","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center of clinical Neuroscience First Faculty of Medicine Charles University and General University Hospital Prague Czech 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Ettenhuber","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Medical Center Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert","family":"Mayer","sequence":"additional","affiliation":[{"name":"Hephata\u2010Klinik Schwalmstadt\u2010Treysa Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Peraita\u2010Adrados","sequence":"additional","affiliation":[{"name":"Sleep and Epilepsy Unit\u2010Clinical Neurophysiology Department Gregorio Mara\u00f1\u00f3n University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Calvo","sequence":"additional","affiliation":[{"name":"Sleep and Epilepsy Unit\u2010Clinical Neurophysiology Department Gregorio Mara\u00f1\u00f3n University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert Jan","family":"Lammers","sequence":"additional","affiliation":[{"name":"Department of Neurology Leiden University Medical Center Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Van der Heide","sequence":"additional","affiliation":[{"name":"Department of Neurology Leiden University Medical Center Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ferini\u2010Strambi","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Universit\u00e0 Vita\u2010Salute San Raffaele Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Plazzi","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences IRCSS Istituto di Scienze Neurologiche University of Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Poli","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences IRCSS Istituto di Scienze Neurologiche University of Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[{"name":"Reference Center for Narcolepsy H\u00f4pital Gui\u2010de\u2010Chauliac INSERM U1061 Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poul","family":"Jennum","sequence":"additional","affiliation":[{"name":"Danish Center for Sleep Medicine Glostrup Hospital and Center of Healthy Aging University of Copenhagen Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helle","family":"Leonthin","sequence":"additional","affiliation":[{"name":"Danish Center for Sleep Medicine Glostrup Hospital and Center of Healthy Aging University of Copenhagen Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Mathis","sequence":"additional","affiliation":[{"name":"Department of Neurology Inselspital Bern University Hospital University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Wierzbicka","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurophysiology Institute of Psychiatry and Neurology Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Puertas","sequence":"additional","affiliation":[{"name":"Sleep Disorders Unit University Hospital La Ribera Alzira Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre A.","family":"Beitinger","sequence":"additional","affiliation":[{"name":"Max Planck Institute of Psychiatry Munich 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