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Impaired time perception has been found in <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>arkinson's disease (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) and attributed to a dysfunctional dopaminergic striatal pacemaker. We aimed to assess time perception in patients with narcolepsy and <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> and to compare the outcome to healthy control participants. Seventeen narcolepsy patients, 12 <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients and 15 healthy controls performed a short time production task, where they had to produce an interval of 1, 2 or 5\u00a0s. The accuracy of time production differed significantly according to task target duration, and there was a trend towards a group difference with narcolepsy patients tending to overproduce all target durations. Absolute variability was significantly different between groups, with narcolepsy patients showing higher absolute variability in comparison to controls and <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients. The analysis of the temporal course of time estimation showed more pronounced overproduction of each target duration at the end of each trial in narcolepsy patients, whereas performance was more or less stable in controls and <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients. Overproduction and higher variability of all time durations in narcolepsy indicate impaired short interval timing in the seconds range, while the scalar property of timing was preserved. The time\u2013course of accuracy and variability of time production within sessions indicate an attention\u2010related mechanism of impaired interval timing.<\/jats:p>","DOI":"10.1111\/jsr.12069","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T19:52:19Z","timestamp":1374695539000},"page":"625-633","source":"Crossref","is-referenced-by-count":6,"title":["Time perception in narcolepsy in comparison to patients with <scp>P<\/scp>arkinson's disease and healthy controls\u2014an exploratory study"],"prefix":"10.1111","volume":"22","author":[{"given":"Rositsa","family":"Poryazova","sequence":"first","affiliation":[{"name":"University Hospital Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armand","family":"Mensen","sequence":"additional","affiliation":[{"name":"Sleep Centre Clinic Barmelweid Barmelweid Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatime","family":"Bislimi","sequence":"additional","affiliation":[{"name":"University Hospital Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana","family":"Huegli","sequence":"additional","affiliation":[{"name":"Sleep Centre Clinic Barmelweid Barmelweid Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian R.","family":"Baumann","sequence":"additional","affiliation":[{"name":"University Hospital Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramin","family":"Khatami","sequence":"additional","affiliation":[{"name":"Sleep Centre Clinic Barmelweid Barmelweid Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1819-06.2006"},{"key":"e_1_2_8_3_1","first-page":"77","article-title":"Validation of a cataplexy questionnaire in 983 sleep\u2010disorders patients","volume":"22","author":"Anic\u2010Labat S.","year":"1999","journal-title":"Sleep"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/115.1.199"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2006.03.003"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70196-4"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000079749"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.1.99"},{"key":"e_1_2_8_9_1","first-page":"171","volume-title":"Time and Mind","author":"Block R. 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